HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.725

Property	Details
Experiments	33961781, 26496610, 18782753, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Hs			1 543
+	Hs
		915267 PP2AB_HUMAN (1-309): 0: 528: 97.41		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		890997 PP4C_HUMAN (4-309): 0: 508: 64.82		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826610 PP2AA_HUMAN (1-309): 0: 529: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826603 PP2AB_HUMAN (1-309): 0: 528: 97.41		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Sc
		618781 PP2A1_YEAST (10-309): 0: 517: 76.00		TCPH_YEAST (2-542): 0: 587: 62.45
+	Sc
		618845 PP2A2_YEAST (10-309): 0: 514: 76.67		TCPH_YEAST (2-542): 0: 587: 62.45
+	Hs
		821161 PP2AA_HUMAN (1-309): 0: 529: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Sc
		618779 PP2A1_YEAST (10-309): 0: 517: 76.00		TCPE_YEAST (2-526): 0: 568: 29.98
+	Hs
		821154 PP2AB_HUMAN (1-309): 0: 528: 97.41		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		826591 PP4C_HUMAN (4-309): 0: 508: 64.82		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573211 PP2AA_HUMAN (1-309): 0: 529: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573203 PP2AB_HUMAN (1-309): 0: 528: 97.41		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821143 PP4C_HUMAN (4-309): 0: 508: 64.82		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Sc
		618772 PP2A1_YEAST (10-309): 0: 517: 76.00		TCPG_YEAST (2-527): 0: 546: 30.68
+	Sc
		618836 PP2A2_YEAST (10-309): 0: 514: 76.67		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		573192 PP4C_HUMAN (4-309): 0: 508: 64.82		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Sc
		594322 PP11_YEAST (11-309): 1.47e-137: 393: 57.71		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		843150 PP2AA_HUMAN (1-309): 0: 529: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843141 PP2AB_HUMAN (1-309): 0: 528: 97.41		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843130 PP4C_HUMAN (4-309): 0: 508: 64.82		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79