HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: CDCA4 (Q9BXL8)
Cell division cycle-associated protein 4 (Hematopoietic progenitor protein)
Gene: CDCA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 241
+	Hs
		915275 PP2AB_HUMAN (1-309): 0: 528: 97.41		CDCA4_HUMAN (1-241): 7.23e-119: 340: 100.00
+	Hs
		891002 PP4C_HUMAN (4-309): 0: 508: 64.82		CDCA4_HUMAN (1-241): 7.23e-119: 340: 100.00
+	Hs
		930842 PP2AA_HUMAN (1-309): 0: 529: 100.00		SRTD2_HUMAN (1-241): 2.73e-78: 240: 24.84
+	Hs
		915187 PP2AB_HUMAN (1-309): 0: 528: 97.41		SRTD2_HUMAN (1-241): 2.73e-78: 240: 24.84
+	Hs
		931031 PP2AA_HUMAN (1-309): 0: 529: 100.00		SRTD1_HUMAN (1-241): 3.69e-47: 158: 21.62