Protein: PR15A
Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)

Gene: PR15A, PPP1R15A
Organism: Homo sapiens
Interactions: 213
UniProt ID: O75807

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

275400

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

6

5

Small-scale

0.954

High

275382

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

5

Small-scale

0.737

High

275401

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

2

5

Small-scale

0.737

High

275363

IF2A
Eukaryotic translation initiation factor 2 subunit 1

4

1

Small-scale

0.683

High

275431

PWP3A
PWWP domain-containing DNA repair factor 3A

2

0

High-throughput

0.602

High

275450

MINK1
Misshapen-like kinase 1

2

0

High-throughput

0.602

High

275469

PKHA1
Pleckstrin homology domain-containing family A member 1

2

0

High-throughput

0.602

High

275371

HSP7C
Heat shock cognate 71 kDa protein

2

3

Small-scale

0.571

High

275414

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.554

High

224247

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.552

High

275365

LYN
Tyrosine-protein kinase Lyn

1

0

Small-scale

0.549

High

275395

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.549

High

275416

PPR1A
Protein phosphatase 1 regulatory subunit 1A

1

0

Small-scale

0.549

High

275464

BAG1
BAG family molecular chaperone regulator 1

1

0

Small-scale

0.549

High

275468

CUED2
CUE domain-containing protein 2

1

0

Small-scale

0.549

High

275448

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

275458

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

167315

SMAD7
Mothers against decapentaplegic homolog 7

1

0

Small-scale

0.529

High

275407

KMT2A
Histone-lysine N-methyltransferase 2A

1

0

Small-scale

0.529

High

275396

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.518

High

158355

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

Small-scale

0.515

High

155969

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

0

High-throughput

0.513

High

275417

CUL3
Cullin-3

1

0

High-throughput

0.513

High

275422

TSN
Translin

1

0

Small-scale

0.504

High

275421

PLEC
Plectin

1

0

High-throughput

0.493

High

275364

JUN
Transcription factor Jun

1

1

Small-scale

0.479

High

275479

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

275461

Z512B
Zinc finger protein 512B

1

1

High-throughput

0.464

High

275442

HABP4
Intracellular hyaluronan-binding protein 4

1

0

Small-scale

0.460

High

275360

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

275380

DDIT3
DNA damage-inducible transcript 3 protein

1

0

Small-scale

0.458

High

275397

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

275405

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

275406

KPCE
Protein kinase C epsilon type

1

0

High-throughput

0.458

High

275446

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

275456

TSC1
Hamartin

1

0

Small-scale

0.458

High

66531

A8K5I0
Epididymis secretory protein Li 103

1

3

High-throughput

0.445

High

66559

A8K781
cDNA FLJ75299, highly similar to Xenopus laevis proteasome

1

2

High-throughput

0.445

High

70371

B2R6X5
cDNA, FLJ93166, highly similar to Homo sapiens heat shock 70kDa protein 6

1

3

High-throughput

0.445

High

70441

B2RBR9
cDNA, FLJ95650, highly similar to Homo sapiens karyopherin

1

1

High-throughput

0.445

High

72082

B3KM81
cDNA FLJ10471 fis, clone NT2RP2000045, highly similar to DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.445

High

72124

B3KS98
Eukaryotic translation initiation factor 3 subunit H

1

2

High-throughput

0.445

High

72909

B4DMA8
Kinesin-like protein

1

1

High-throughput

0.445

High

72917

B4DMZ9
Cyclic AMP-responsive element-binding protein 3-like protein 4

1

1

High-throughput

0.445

High

72933

B4DNN2
DnaJ

1

1

High-throughput

0.445

High

81621

B7Z4V2
Stress-70 protein, mitochondrial

1

5

High-throughput

0.445

High

127142

IPO5
Importin-5

1

1

High-throughput

0.445

High

166649

CE290
Centrosomal protein of 290 kDa

1

1

High-throughput

0.445

High

225821

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

1

High-throughput

0.445

High

243224

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.445

High

275370

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.445

High

275373

K1C10
Keratin, type I cytoskeletal 10

1

1

High-throughput

0.445

High

275374

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.445

High

275375

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.445

High

275377

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.445

High

275378

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

2

High-throughput

0.445

High

275381

K22E
Keratin, type II cytoskeletal 2 epidermal

1

1

High-throughput

0.445

High

275385

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.445

High

275387

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.445

High

275388

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

2

High-throughput

0.445

High

275389

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.445

High

275392

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.445

High

275402

PRS8
26S proteasome regulatory subunit 8

1

1

High-throughput

0.445

High

275403

PRS10
26S proteasome regulatory subunit 10B

1

1

High-throughput

0.445

High

275420

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

1

High-throughput

0.445

High

275427

Q1KLZ0
Actin, cytoplasmic 1

1

1

High-throughput

0.445

High

275429

Q2I0Y7
Casein kinase II subunit alpha

1

1

High-throughput

0.445

High

275433

TBB8
Tubulin beta-8 chain

1

1

High-throughput

0.445

High

275437

Q53XC0
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.445

High

275438

ACTBL
Beta-actin-like protein 2

1

1

High-throughput

0.445

High

275444

Q6I9V5
ADP/ATP translocase

1

1

High-throughput

0.445

High

275453

RN138
E3 ubiquitin-protein ligase RNF138

1

1

High-throughput

0.445

High

275457

HS105
Heat shock protein 105 kDa

1

3

High-throughput

0.445

High

275459

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.445

High

275463

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.445

High

275465

MICU1
Calcium uptake protein 1, mitochondrial

1

1

High-throughput

0.445

High

275466

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.445

High

275470

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.445

High

275475

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

1

High-throughput

0.445

High

275480

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.445

High

275481

DDX52
Probable ATP-dependent RNA helicase DDX52

1

1

High-throughput

0.445

High

48204

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.426

High

48578

A0JLN5
Translocation protein SEC62

1

0

High-throughput

0.426

High

66230

A8K0T9
F-actin-capping protein subunit alpha

1

0

High-throughput

0.426

High

66776

A8KA19
Exportin-T

1

0

High-throughput

0.426

High

69775

B1ANR0
Polyadenylate-binding protein

1

0

High-throughput

0.426

High

70008

B1Q2B0
URCC5

1

0

High-throughput

0.426

High

70444

B2RBS8
Albumin

1

0

High-throughput

0.426

High

70476

B2RDW1
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

70485

B2RMQ4
Cytoskeleton associated protein 2

1

0

High-throughput

0.426

High

72101

B3KP95
cDNA FLJ31463 fis, clone NT2NE2001326, highly similar to Exonuclease 3'-5' domain-like-containing protein 2

1

0

High-throughput

0.426

High

72102

B3KPC1
Protein pelota homolog

1

0

High-throughput

0.426

High

72120

B3KRS1
Gamma-tubulin complex component

1

0

High-throughput

0.426

High

72121

B3KRV2
non-specific serine/threonine protein kinase

1

0

High-throughput

0.426

High

72460

B4DDF7
cDNA FLJ53296, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.426

High

72889

B4DKS0
cDNA FLJ53381, highly similar to Monocarboxylate transporter 1

1

0

High-throughput

0.426

High

72957

B4DQE5
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

73102

B4DY09
Interleukin enhancer binding factor 2

1

0

High-throughput

0.426

High

117535

MYO1C
Unconventional myosin-Ic

1

0

High-throughput

0.426

High

118820

GTPB1
GTP-binding protein 1

1

0

High-throughput

0.426

High

121645

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.426

High

133262

NOP56
Nucleolar protein 56

1

0

High-throughput

0.426

High

133795

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

High-throughput

0.426

High

147585

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

0

High-throughput

0.426

High

151667

IRS4
Insulin receptor substrate 4

1

0

High-throughput

0.426

High

154108

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.426

High

174024

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.426

High

209542

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.426

High

271500

ERAL1
GTPase Era, mitochondrial

1

0

High-throughput

0.426

High

275356

TOM70
Mitochondrial import receptor subunit TOM70

1

0

High-throughput

0.426

High

275357

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.426

High

275359

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.426

High

275361

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.426

High

275362

K2C1
Keratin, type II cytoskeletal 1

1

0

High-throughput

0.426

High

275366

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.426

High

275367

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.426

High

275369

COT1
COUP transcription factor 1

1

0

High-throughput

0.426

High

275372

EF2
Elongation factor 2

1

0

High-throughput

0.426

High

275379

K1C9
Keratin, type I cytoskeletal 9

1

0

High-throughput

0.426

High

275383

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.426

High

275384

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.426

High

275386

RT29
Small ribosomal subunit protein mS29

1

0

High-throughput

0.426

High

275390

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

275391

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.426

High

275393

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

0

High-throughput

0.426

High

275394

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.426

High

275398

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.426

High

275399

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.426

High

275404

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.426

High

275409

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.426

High

275413

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.426

High

275418

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

275419

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.426

High

275424

PDCD2
Programmed cell death protein 2

1

0

High-throughput

0.426

High

275425

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

275428

Q1MSW8
Cellular tumor antigen p53

1

0

High-throughput

0.426

High

275432

Q2TSD0
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.426

High

275434

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.426

High

275435

Q4KMX3
JPH1 protein

1

0

High-throughput

0.426

High

275436

Q53SS8
Epididymis secretory protein Li 85

1

0

High-throughput

0.426

High

275445

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.426

High

275447

SLN11
Schlafen family member 11

1

0

High-throughput

0.426

High

275449

T183A
Transmembrane protein 183A

1

0

High-throughput

0.426

High

275451

ABCF1
ATP-binding cassette sub-family F member 1

1

0

High-throughput

0.426

High

275455

THAP4
Peroxynitrite isomerase THAP4

1

0

High-throughput

0.426

High

275471

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.426

High

275473

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.426

High

275476

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.426

High

275477

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.426

High

275478

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.426

High

275483

LAS1L
Ribosomal biogenesis protein LAS1L

1

0

High-throughput

0.426

High

59498

A4D110
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.407

High

59854

A4D210
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.407

High

70348

B2R5W2
cDNA, FLJ92657, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein C

1

1

High-throughput

0.407

High

70379

B2R7J8
cDNA, FLJ93474, Homo sapiens zinc finger protein 205

1

2

High-throughput

0.407

High

70433

B2RAX6
cDNA, FLJ95176, Homo sapiens CGI-48 protein

1

1

High-throughput

0.407

High

70438

B2RBI0
Fatty acyl-CoA reductase

1

1

High-throughput

0.407

High

70467

B2RDG1
Fatty acyl-CoA reductase

1

1

High-throughput

0.407

High

72128

B3KSH1
Eukaryotic translation initiation factor 3 subunit F

1

1

High-throughput

0.407

High

72174

B3KSQ7
Drebrin 1, isoform CRA_d

1

1

High-throughput

0.407

High

72216

B3KSX3
cDNA FLJ37224 fis, clone BRAMY2000052, moderately similar to RNA-binding protein Raly

1

1

High-throughput

0.407

High

72392

B3KX11
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

72891

B4DL07
cDNA FLJ53353, highly similar to ATP-binding cassette sub-family D member 3

1

1

High-throughput

0.407

High

72916

B4DMY3
cDNA FLJ60713, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein A/B

1

2

High-throughput

0.407

High

73059

B4DV95
mitogen-activated protein kinase kinase

1

1

High-throughput

0.407

High

275415

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.407

High

275423

PCH2
Pachytene checkpoint protein 2 homolog

1

2

High-throughput

0.407

High

275439

Q562V5
Actin-like protein

1

1

High-throughput

0.407

High

275440

Q59EY3
Sp1 transcription factor variant

1

1

High-throughput

0.407

High

275452

Q8TA92
Similar to AFG3 ATPase family gene 3-like 2

1

1

High-throughput

0.407

High

275460

MAGD4
Melanoma-associated antigen D4

1

1

High-throughput

0.407

High

275482

ZN281
Zinc finger protein 281

1

1

High-throughput

0.407

High

275358

RPP29
Ribonuclease P protein subunit p29

2

0

High-throughput

0.328

High

275408

ZNF92
Zinc finger protein 92

2

0

High-throughput

0.328

High

275454

BBX
HMG box transcription factor BBX

2

0

High-throughput

0.328

High

275412

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

0

Small-scale

0.325

High

275376

PO3F3
POU domain, class 3, transcription factor 3

1

0

High-throughput

0.238

Low

48072

A0AVN2
BRCA1 associated RING domain 1

1

0

High-throughput

0.232

Low

56448

A2A2Q9
Protein AAR2 homolog

1

0

High-throughput

0.232

Low

57898

KV229
Immunoglobulin kappa variable 2-29

1

0

High-throughput

0.232

Low

66346

A8K2R3
cDNA FLJ75083, highly similar to Homo sapiens amine oxidase

1

0

High-throughput

0.232

Low

66627

A8K8U7
cDNA FLJ78640, highly similar to Homo sapiens TSPY-like 2

1

0

High-throughput

0.232

Low

69548

B0QY89
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.232

Low

69759

B1AKY9
Sodium/potassium-transporting ATPase subunit alpha

1

0

High-throughput

0.232

Low

70350

B2R5Y4
cDNA, FLJ92684, highly similar to Homo sapiens IK cytokine, down-regulator of HLA II

1

0

High-throughput

0.232

Low

70363

B2R6F9
cDNA, FLJ92932, highly similar to Homo sapiens serine/threonine kinase 38

1

0

High-throughput

0.232

Low

70376

B2R7C5
DNA replication licensing factor MCM3

1

0

High-throughput

0.232

Low

70384

B2R806
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.232

Low

70430

B2RAR2
RNA-binding protein NOB1

1

0

High-throughput

0.232

Low

70458

B2RD09
cDNA, FLJ96406, highly similar to Homo sapiens NOL1/NOP2/Sun domain family, member 5

1

0

High-throughput

0.232

Low

70469

B2RDI7
E3 ubiquitin-protein ligase RNF10

1

0

High-throughput

0.232

Low

72098

B3KNN7
cDNA FLJ30049 fis, clone ADRGL1000033, highly similar to 26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.232

Low

72241

B3KU03
cDNA FLJ39022 fis, clone NT2RP7003724, weakly similar to Serine/arginine repetitive matrix protein 1

1

0

High-throughput

0.232

Low

72403

B3KY60
cDNA FLJ16777 fis, clone BRHIP2029567, highly similar to Cell division cycle 5-like protein

1

0

High-throughput

0.232

Low

72808

B4DIS6
RNA helicase

1

0

High-throughput

0.232

Low

72894

B4DLG2
cDNA FLJ58196, highly similar to Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.232

Low

73066

B4DWV9
cDNA FLJ53108, highly similar to Guanine nucleotide-binding protein alpha-13 subunit

1

0

High-throughput

0.232

Low

78143

B5BUB1
RuvB-like helicase

1

0

High-throughput

0.232

Low

81651

B7Z720
E74-like factor 2

1

0

High-throughput

0.232

Low

123151

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.232

Low

259320

DUS11
RNA/RNP complex-1-interacting phosphatase

1

0

High-throughput

0.232

Low

275368

H2A1
Histone H2A type 1

1

0

High-throughput

0.232

Low

275410

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.232

Low

275411

Q0QEN7
ATP synthase subunit beta

1

0

High-throughput

0.232

Low

275426

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.232

Low

275430

Q2M1J6
Oxidase

1

0

High-throughput

0.232

Low

275441

NOM1
Nucleolar MIF4G domain-containing protein 1

1

0

High-throughput

0.232

Low

275443

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.232

Low

275462

SNX18
Sorting nexin-18

1

0

High-throughput

0.232

Low

275467

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

275472

ZN629
Zinc finger protein 629

1

0

High-throughput

0.232

Low

275474

NUFP1
FMR1-interacting protein NUFIP1

1

0

High-throughput

0.232

Low

275484

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024