HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1278
+	Hs
		891760 ACTB_HUMAN (4-377): 0: 599: 94.12		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		929862 ACTG_HUMAN (4-377): 0: 599: 94.39		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		915383 ACTA_HUMAN (1-377): 0: 596: 98.41		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		725136 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Rn
		892236 ACTB_RAT (4-377): 0: 599: 94.12		MYH10_RAT (664-1275): 1.11e-22: 107: 10.46
+	Hs
		725135 ACTH_HUMAN (4-377): 0: 591: 98.93		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		724738 ACTB_HUMAN (4-377): 0: 599: 94.12		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		724762 ACTG_HUMAN (4-377): 0: 599: 94.39		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		724766 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		724767 ACTS_HUMAN (1-377): 0: 599: 98.94		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Mm
		892205 ACTB_MOUSE (4-377): 0: 599: 94.12		MYH9_MOUSE (826-1275): 8.37e-15: 82.2: 10.13
+	Rn
		892228 ACTB_RAT (4-377): 0: 599: 94.12		MYH9_RAT (805-1277): 3.43e-14: 80.2: 12.76