Protein: HPHL1
Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1)

Gene: HPHL1, HEPHL1
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q6MZM0

Gene Ontology (top 5):
GO:0004322 - ferroxidase activity
GO:0005507 - copper ion binding
GO:0005886 - plasma membrane
GO:0006825 - copper ion transport
GO:0006826 - iron ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1154370

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.638

High

1154388

O51E2
Olfactory receptor 51E2

3

0

High-throughput

0.638

High

1154368

GPBP1
Vasculin

2

0

High-throughput

0.602

High

1154374

IL31R
Interleukin-31 receptor subunit alpha

2

0

High-throughput

0.602

High

1154377

FAN
Protein FAN

2

1

High-throughput

0.574

High

1154381

RM38
Large ribosomal subunit protein mL38

2

1

High-throughput

0.574

High

686682

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

882751

STX17
Syntaxin-17

1

1

High-throughput

0.536

High

1032194

ITAD
Integrin alpha-D

1

1

High-throughput

0.536

High

281993

ANXA9
Annexin A9

1

0

High-throughput

0.513

High

714920

BTC
Probetacellulin [Cleaved into: Betacellulin

1

0

High-throughput

0.513

High

1153645

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

0

High-throughput

0.513

High

1154365

NPSR1
Neuropeptide S receptor

1

0

High-throughput

0.513

High

1154382

DTBP1
Dysbindin

1

0

High-throughput

0.513

High

1154386

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

0

High-throughput

0.513

High

1154391

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

0

High-throughput

0.513

High

1045049

CD166
CD166 antigen

1

0

High-throughput

0.493

High

958705

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

1154380

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.489

High

1154385

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.489

High

1154392

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.489

High

1154400

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

1154403

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

1122391

SGO2
Shugoshin 2

3

0

High-throughput

0.347

High

1132390

TEX35
Testis-expressed protein 35

3

0

High-throughput

0.347

High

1153846

IFIX
Pyrin and HIN domain-containing protein 1

3

0

High-throughput

0.347

High

1154369

DOPP1
Dolichyldiphosphatase 1

3

0

High-throughput

0.347

High

1154378

TFG
Protein TFG

3

0

High-throughput

0.347

High

1154379

PMM1
Phosphomannomutase 1

3

0

High-throughput

0.347

High

1154383

MTNB
Methylthioribulose-1-phosphate dehydratase

3

0

High-throughput

0.347

High

1154396

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.347

High

390955

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.328

High

970627

SEMG2
Semenogelin-2

2

0

High-throughput

0.328

High

1154376

CPLX3
Complexin-3

2

0

High-throughput

0.328

High

1154384

SETB2
Histone-lysine N-methyltransferase SETDB2

2

0

High-throughput

0.328

High

1154390

ZMAT4
Zinc finger matrin-type protein 4

2

0

High-throughput

0.328

High

1154394

TBC14
TBC1 domain family member 14

2

0

High-throughput

0.328

High

1154399

FBXL4
F-box/LRR-repeat protein 4

2

0

High-throughput

0.328

High

1154401

OAZ3
Ornithine decarboxylase antizyme 3

2

0

High-throughput

0.328

High

1154404

KIF3A
Kinesin-like protein KIF3A

2

0

High-throughput

0.328

High

1023380

COASY
Bifunctional coenzyme A synthase

2

0

High-throughput

0.318

High

1079926

RB11B
Ras-related protein Rab-11B

2

0

High-throughput

0.318

High

49098

DHR12
Dehydrogenase/reductase SDR family member 12

1

0

High-throughput

0.279

Low

127110

FOXN3
Forkhead box protein N3

1

0

High-throughput

0.279

Low

267009

SRS10
Serine/arginine-rich splicing factor 10

1

0

High-throughput

0.279

Low

303690

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

304975

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

345464

FOS
Protein c-Fos

1

0

High-throughput

0.279

Low

439135

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

708229

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

813070

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.279

Low

821574

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

1017584

FSTL1
Follistatin-related protein 1

1

0

High-throughput

0.279

Low

1124723

YIF1B
Protein YIF1B

1

0

High-throughput

0.279

Low

1127359

CX066
Uncharacterized protein CXorf66

1

0

High-throughput

0.279

Low

1133352

TMTC4
Protein O-mannosyl-transferase TMTC4

1

0

High-throughput

0.279

Low

1154366

HEPN1
Putative cancer susceptibility gene HEPN1 protein

1

0

High-throughput

0.279

Low

1154367

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1154371

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

1154372

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.279

Low

1154373

BHE23
Class E basic helix-loop-helix protein 23

1

0

High-throughput

0.279

Low

1154375

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

1154387

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.279

Low

1154389

SRMS
Tyrosine-protein kinase Srms

1

0

High-throughput

0.279

Low

1154393

KLH11
Kelch-like protein 11

1

0

High-throughput

0.279

Low

1154395

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.279

Low

1154397

DPOG2
DNA polymerase subunit gamma-2

1

0

High-throughput

0.279

Low

1154398

FBX3
F-box only protein 3

1

0

High-throughput

0.279

Low

1154402

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

0

High-throughput

0.279

Low

298587

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

903304

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024