HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: MED1 (Q15648)
Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
Gene: MED1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30890647
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010628 - positive regulation of gene expression GO:0016020 - membrane GO:0043066 - negative regulation of apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1581
+	Hs
		554290 ACTA_HUMAN (1-377): 0: 596: 98.41		MUC1_HUMAN (743-1574): 5.56e-38: 158: 8.83
+	Hs
		932156 ACTC_HUMAN (1-377): 0: 599: 100.00		MDC1_HUMAN (751-1577): 1.19e-16: 88.6: 8.40
+	Hs
		891686 ACTB_HUMAN (4-377): 0: 599: 94.12		MAP1A_HUMAN (785-1483): 6.37e-10: 66.6: 11.64
+	Hs
		891853 ACTB_HUMAN (4-377): 0: 599: 94.12		SRCAP_HUMAN (539-1053): 4.95e-09: 63.6: 11.43
+	Hs
		929905 ACTG_HUMAN (4-377): 0: 599: 94.39		SRCAP_HUMAN (539-1053): 4.95e-09: 63.6: 11.43
+	Hs
		932219 ACTC_HUMAN (1-377): 0: 599: 100.00		SRCAP_HUMAN (539-1053): 4.95e-09: 63.6: 11.43
+	Hs
		891699 ACTB_HUMAN (4-377): 0: 599: 94.12		ANK2_HUMAN (662-1563): 9.43e-09: 62.7: 11.52
+	Hs
		930079 ACTH_HUMAN (4-377): 0: 591: 98.93		ANK2_HUMAN (662-1563): 9.43e-09: 62.7: 11.52