HitPredict

Interactor 1: RACK1 (P68040)
Small ribosomal subunit protein RACK1 (12-3) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) (Receptor of activated protein kinase C 1) (p205) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Interactor 2: FZR1 (Q9R1K5)
Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)
Gene: FZR1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32434143
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Mm			1 493
+	Hs
		903109 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		WDR5_HUMAN (300-493): 7.33e-56: 191: 19.49
+	Hs
		929610 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		SNR40_HUMAN (8-339): 3.05e-51: 179: 14.78
+	Hs
		929579 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		POC1B_HUMAN (49-259): 1.18e-34: 137: 13.95
+	Hs
		792967 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		LIS1_HUMAN (351-493): 3.75e-33: 131: 17.36
+	Hs
		929603 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		FBXW7_HUMAN (340-493): 9.46e-31: 128: 16.77
+	Hs
		929717 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		FZR1_HUMAN (319-492): 5.23e-19: 91.5: 19.55
+	Hs
		921518 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		GBB2_HUMAN (329-478): 9.4e-15: 77.4: 18.07
+	Hs
		929692 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		NLE1_HUMAN (3-174): 3.44e-13: 73.4: 13.37
+	Dm
		1358845 WDS_DROME (3-223): 1.09e-62: 204: 25.78		WDS_DROME (300-493): 5.69e-55: 189: 20.51
+	Hs
		903077 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		WDR5_HUMAN (300-493): 7.33e-56: 191: 19.49
+	Hs
		903349 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		WDR5B_HUMAN (299-493): 7.06e-53: 183: 18.88
+	Hs
		903428 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		SNR40_HUMAN (8-339): 3.05e-51: 179: 14.78
+	Hs
		792949 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		LIS1_HUMAN (351-493): 3.75e-33: 131: 17.36
+	Hs
		903418 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		FBXW7_HUMAN (340-493): 9.46e-31: 128: 16.77
+	Dm
		1358859 WDS_DROME (3-223): 1.09e-62: 204: 25.78		FBXW7_DROME (114-292): 1.43e-18: 91.2: 14.29
+	Hs
		903603 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		FZR1_HUMAN (319-492): 5.23e-19: 91.5: 19.55
+	Hs
		792935 LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43		LIS1_HUMAN (351-493): 3.75e-33: 131: 17.36
+	Mm
		925836 LIS1_MOUSE (144-316): 4.89e-46: 162: 23.43		LIS1_MOUSE (351-493): 3.11e-33: 131: 17.36
+	Hs
		903176 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		CDC20_HUMAN (361-493): 4.11e-13: 73.4: 16.91
+	Hs
		903551 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		NLE1_HUMAN (3-174): 3.44e-13: 73.4: 13.37