Protein: DOT6
Transcriptional regulatory protein DOT6 (Disrupter of telomere silencing protein 6) (PAC-binding factor 2)

Gene: DOT6
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: P40059

Gene Ontology (top 5):
GO:0000183 - rDNA heterochromatin formation
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366361

HSP82
ATP-dependent molecular chaperone HSP82

3

0

High-throughput

0.613

High

515182

SCH9
Serine/threonine-protein kinase SCH9

1

1

Small-scale

0.569

High

767474

RXT3
Transcriptional regulatory protein RXT3

2

0

High-throughput

0.563

High

767476

CTI6
Histone deacetylase complex subunit CTI6

2

1

Small-scale

0.552

High

511478

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.536

High

676087

XPO1
Exportin-1

1

0

High-throughput

0.513

High

767468

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

412765

KAPA
cAMP-dependent protein kinase type 1

1

0

Small-scale

0.504

High

767465

NST1
Stress response protein NST1

1

0

High-throughput

0.493

High

662345

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

688764

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.479

High

767463

SDS3
Transcriptional regulatory protein SDS3

1

1

Small-scale

0.479

High

767469

GIS1
Transcriptional activator/repressor GIS1

1

1

High-throughput

0.479

High

767471

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

767473

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

767475

SGO1
Shugoshin

1

1

High-throughput

0.479

High

767478

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

767479

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.479

High

410394

SC160
Protein SCP160

1

0

High-throughput

0.458

High

650302

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

716252

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

767464

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.458

High

767466

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

767467

MOT3
Transcriptional activator/repressor MOT3

1

0

High-throughput

0.458

High

767470

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

767472

PAL1
Protein PAL1

1

0

High-throughput

0.458

High

767477

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

491360

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

494080

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

767460

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

767461

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

609093

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

645046

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.249

Low

745675

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

757986

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

767462

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024