HitPredict

Interactor 1: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EFG_C~GTP_EFTU, EFG_III~GTP_EFTU, EFG_IV~GTP_EFTU, EFTUD2~GTP_EFTU, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, EFG_III~GTP_EFTU_D2, EFTUD2~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU_D3, GTP_EFTU_D2~GTP_EFTU_D3
Common GO terms	GO:0003723 - RNA binding GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005634 - nucleus GO:0005829 - cytosol and 1 others more... GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 972
+	Hs
		545857 ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064889 HBS1L_HUMAN (5-443): 5.78e-158: 464: 38.95		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		531115 EF1A1_HUMAN (1-462): 0: 578: 100.00		EF2_HUMAN (111-957): 0: 915: 38.16
+	Sc
		367837 EF1A_YEAST (1-445): 0: 538: 80.90		EF2_YEAST (111-957): 0: 879: 36.04
+	Zm
		5859 O50018_MAIZE (1-448): 0: 518: 77.23		A0A1D6E4M0_MAIZE (120-924): 0: 579: 20.35