Protein: ISLR2
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein)

Gene: ISLR2
Organism: Homo sapiens
Interactions: 14
UniProt ID: Q6UXK2

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007399 - nervous system development
GO:0009986 - cell surface
GO:0045773 - positive regulation of axon extension

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1115745

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.691

High

1249935

TLK2
Serine/threonine-protein kinase tousled-like 2

1

4

High-throughput

0.618

High

412125

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

932693

EMP1
Epithelial membrane protein 1

2

1

High-throughput

0.606

High

1159473

NKG7
Protein NKG7

2

0

High-throughput

0.580

High

1249936

LAP4B
Lysosomal-associated transmembrane protein 4B

2

0

High-throughput

0.580

High

1249937

MRAP2
Melanocortin-2 receptor accessory protein 2

2

0

High-throughput

0.580

High

295688

UPK1B
Uroplakin-1b

2

3

High-throughput

0.553

High

255081

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

529981

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

906296

GPC3
Glypican-3

1

4

High-throughput

0.445

High

1119174

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

1141186

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.437

High

516268

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025