HitPredict

Interactor 1: E9PXB7 (E9PXB7)
E3 ubiquitin-protein ligase (EC 2.3.2.26)
Gene: Nedd4l

Interactor 2: SCNNG (Q9WU39)
Amiloride-sensitive sodium channel subunit gamma (Epithelial Na(+) channel subunit gamma) (Gamma-ENaC) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG)
Gene: Scnn1g

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.550

Property	Details
Experiments	12424229, 15123669
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Mm			1 655
+	Hs
		845991 NED4L_HUMAN (1-835): 0: 944: 95.79		SCNNG_HUMAN (1-655): 0: 787: 85.50
+	Hs
		808050 NEDD4_HUMAN (1-835): 0: 845: 60.41		SCNNG_HUMAN (1-655): 0: 787: 85.50
+	Hs
		739604 NED4L_HUMAN (1-835): 0: 944: 95.79		SCNNA_HUMAN (24-636): 0: 636: 33.17
+	Mm
		93272 E9PXB7_MOUSE (1-835): 0: 959: 100.00		SCNNA_MOUSE (24-629): 0: 618: 33.66
+	Rn
		739630 Q4V8H7_RAT (34-832): 0: 762: 36.59		SCNNG_RAT (1-655): 0: 805: 96.49
+	Mm
		93285 E9PXB7_MOUSE (1-835): 0: 959: 100.00		SCNNB_MOUSE (18-639): 0: 596: 36.13
+	Mm
		1208291 NED4L_MOUSE (1-835): 0: 951: 97.54		SCNNB_MOUSE (18-639): 0: 596: 36.13
+	Hs
		845978 NED4L_HUMAN (1-835): 0: 944: 95.79		SCNNB_HUMAN (18-639): 0: 603: 36.81
+	Hs
		739582 NEDD4_HUMAN (1-835): 0: 845: 60.41		SCNNA_HUMAN (24-636): 0: 636: 33.17
+	Hs
		808049 NEDD4_HUMAN (1-835): 0: 845: 60.41		SCNNB_HUMAN (18-639): 0: 603: 36.81
+	Hs
		739597 HUWE1_HUMAN (286-833): 3.77e-170: 548: 34.17		SCNNA_HUMAN (24-636): 0: 636: 33.17
+	Mm
		808383 NEDD4_MOUSE (10-135): 2.3e-17: 89.1: 16.67		SCNNG_MOUSE (1-655): 0: 818: 100.00
+	Hs
		125257 WWP2_HUMAN (24-172): 1.78e-20: 99.1: 20.00		SCNNG_HUMAN (1-655): 0: 787: 85.50
+	Hs
		739608 WWP1_HUMAN (6-182): 1.18e-28: 125: 22.28		SCNNA_HUMAN (24-636): 0: 636: 33.17
+	Hs
		125197 WWP2_HUMAN (24-172): 1.78e-20: 99.1: 20.00		SCNNA_HUMAN (24-636): 0: 636: 33.17
+	Hs
		739596 HECW1_HUMAN (153-500): 2.68e-18: 92.6: 16.54		SCNNA_HUMAN (24-636): 0: 636: 33.17
+	Mm
		808356 NEDD4_MOUSE (10-135): 2.3e-17: 89.1: 16.67		SCNNA_MOUSE (24-629): 0: 618: 33.66
+	Hs
		125256 WWP2_HUMAN (24-172): 1.78e-20: 99.1: 20.00		SCNNB_HUMAN (18-639): 0: 603: 36.81
+	Hs
		845975 HECW1_HUMAN (153-500): 2.68e-18: 92.6: 16.54		SCNNB_HUMAN (18-639): 0: 603: 36.81
+	Mm
		808382 NEDD4_MOUSE (10-135): 2.3e-17: 89.1: 16.67		SCNNB_MOUSE (18-639): 0: 596: 36.13