HitPredict

Interactor 1: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Interactor 2: SNAG (Q99747)
Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma)
Gene: NAPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.950

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311, 30833792, 40437099
Identification Methods	affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~SNAP
Common GO terms	GO:0005483 - soluble NSF attachment protein activity GO:0006886 - intracellular protein transport GO:0006891 - intra-Golgi vesicle-mediated transport GO:0019905 - syntaxin binding GO:0061025 - membrane fusion and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 312
+	Hs
		1407042 SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25		SNAG_HUMAN (1-312): 3.67e-87: 265: 100.00
+	Hs
		933051 SNAA_HUMAN (1-295): 2.14e-113: 330: 100.00		SNAB_HUMAN (3-281): 7.2e-68: 215: 21.11
+	Dm
		1171615 SNAP_DROME (5-295): 7.88e-105: 308: 61.51		Q9U6R9_DROME (1-312): 3.87e-71: 224: 38.14
+	Dm
		1171622 SNAP_DROME (5-295): 7.88e-105: 308: 61.51		Q9VH25_DROME (1-290): 3.11e-59: 193: 29.66
+	Hs
		1407036 SNAG_HUMAN (4-265): 6.78e-68: 215: 23.40		SNAG_HUMAN (1-312): 3.67e-87: 265: 100.00
+	Dm
		1458074 Q9U6R9_DROME (4-265): 3.86e-58: 190: 18.49		Q9U6R9_DROME (1-312): 3.87e-71: 224: 38.14
+	Dm
		1458081 Q9U6R9_DROME (4-265): 3.86e-58: 190: 18.49		Q9VH25_DROME (1-290): 3.11e-59: 193: 29.66