Protein: SNAA
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)

Gene: SNAA, NAPA
Organism: Homo sapiens
Interactions: 166
UniProt ID: P54920

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005483 - soluble NSF attachment protein activity
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006891 - intra-Golgi vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

189479

STX7
Syntaxin-7

8

20

Small-scale

0.969

High

933028

STX12
Syntaxin-12

7

20

Small-scale

0.963

High

278485

VAMP4
Vesicle-associated membrane protein 4

6

19

High-throughput

0.950

High

933048

SNAG
Gamma-soluble NSF attachment protein

6

7

High-throughput

0.950

High

857070

NSF
Vesicle-fusing ATPase

6

10

Small-scale

0.950

High

933003

STX5
Syntaxin-5

5

20

Small-scale

0.935

High

933073

STX8
Syntaxin-8

5

20

Small-scale

0.927

High

932999

STX4
Syntaxin-4

4

20

High-throughput

0.917

High

225975

STX6
Syntaxin-6

4

19

High-throughput

0.903

High

160876

STX16
Syntaxin-16

3

20

High-throughput

0.871

High

249837

STX10
Syntaxin-10

3

20

High-throughput

0.871

High

933010

VAMP3
Vesicle-associated membrane protein 3

3

20

High-throughput

0.871

High

932991

VAMP2
Vesicle-associated membrane protein 2

3

20

Small-scale

0.866

High

933050

VAMP8
Vesicle-associated membrane protein 8

3

20

Small-scale

0.866

High

280163

SC22B
Vesicle-trafficking protein SEC22b

4

20

High-throughput

0.813

High

192222

YKT6
Synaptobrevin homolog YKT6

2

19

High-throughput

0.811

High

328650

VAMP5
Vesicle-associated membrane protein 5

2

20

High-throughput

0.811

High

907987

VAMP7
Vesicle-associated membrane protein 7

2

20

High-throughput

0.811

High

933034

STXB6
Syntaxin-binding protein 6

2

1

High-throughput

0.811

High

933051

SNAB
Beta-soluble NSF attachment protein

2

7

High-throughput

0.811

High

286636

STX11
Syntaxin-11

2

20

High-throughput

0.776

High

933004

STX3
Syntaxin-3

2

20

High-throughput

0.776

High

933012

STX1A
Syntaxin-1A

2

20

Small-scale

0.768

High

933069

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

6

13

High-throughput

0.736

High

179858

BET1
BET1 homolog

5

16

High-throughput

0.718

High

124019

SNP23
Synaptosomal-associated protein 23

4

16

High-throughput

0.710

High

933043

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

4

13

High-throughput

0.699

High

933068

STX18
Syntaxin-18

4

5

High-throughput

0.697

High

933040

SCFD1
Sec1 family domain-containing protein 1

3

9

High-throughput

0.675

High

933062

VPS45
Vacuolar protein sorting-associated protein 45

3

9

High-throughput

0.675

High

331850

GOSR1
Golgi SNAP receptor complex member 1

3

5

High-throughput

0.667

High

933019

RINT1
RAD50-interacting protein 1

3

0

High-throughput

0.646

High

933065

USE1
Vesicle transport protein USE1

4

4

High-throughput

0.638

High

60320

NBAS
NBAS subunit of NRZ tethering complex

2

1

High-throughput

0.628

High

160251

GOSR2
Golgi SNAP receptor complex member 2

2

13

High-throughput

0.628

High

343338

SNP29
Synaptosomal-associated protein 29

2

16

High-throughput

0.628

High

933038

SCFD2
Sec1 family domain-containing protein 2

2

1

High-throughput

0.628

High

932983

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.618

High

933001

SEC20
Vesicle transport protein SEC20

3

4

High-throughput

0.616

High

211767

ZW10
Centromere/kinetochore protein zw10 homolog

2

0

High-throughput

0.602

High

619641

VCAM1
Vascular cell adhesion protein 1

2

3

High-throughput

0.601

High

488756

FURIN
Furin

1

0

Small-scale

0.549

High

249113

DSCAM
Cell adhesion molecule DSCAM

1

1

High-throughput

0.541

High

415458

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

125723

STXB3
Syntaxin-binding protein 3

1

9

High-throughput

0.536

High

389183

FINC
Fibronectin

1

3

High-throughput

0.536

High

932990

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.536

High

933002

PAK2
Serine/threonine-protein kinase PAK 2

1

1

High-throughput

0.536

High

933015

ODR4
Protein odr-4 homolog

1

1

High-throughput

0.536

High

933016

STXB5
Syntaxin-binding protein 5

1

1

High-throughput

0.536

High

933020

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.536

High

933027

UBE3B
Ubiquitin-protein ligase E3B

1

1

High-throughput

0.536

High

933064

BET1L
BET1-like protein

1

14

High-throughput

0.536

High

933076

GOT1B
Vesicle transport protein GOT1B

1

1

High-throughput

0.536

High

588305

RFA2
Replication protein A 32 kDa subunit

2

1

High-throughput

0.533

High

767794

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.533

High

933060

RTN4
Reticulon-4

1

0

High-throughput

0.518

High

843416

HD
Huntingtin

1

4

High-throughput

0.515

High

62048

WDR91
WD repeat-containing protein 91

1

0

High-throughput

0.513

High

178925

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.513

High

365342

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.513

High

466015

ANXA6
Annexin A6

1

0

High-throughput

0.513

High

877309

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.513

High

923460

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

1

0

High-throughput

0.513

High

932996

TOP2B
DNA topoisomerase 2-beta

1

0

High-throughput

0.513

High

933009

ELOB
Elongin-B

1

0

High-throughput

0.513

High

933013

WDR81
WD repeat-containing protein 81

1

0

High-throughput

0.513

High

933024

CYS1
Cystin-1

1

0

High-throughput

0.513

High

933025

MAEA
E3 ubiquitin-protein transferase MAEA

1

0

High-throughput

0.513

High

933033

T185A
Transmembrane protein 185A

1

0

High-throughput

0.513

High

933037

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.513

High

933041

RREB1
Ras-responsive element-binding protein 1

1

0

High-throughput

0.513

High

933046

SERC2
Serine incorporator 2

1

0

High-throughput

0.513

High

933049

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.513

High

933055

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.513

High

933056

RBSK
Ribokinase

1

0

High-throughput

0.513

High

933058

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.513

High

933061

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

933067

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.513

High

421788

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

932987

SNP25
Synaptosomal-associated protein 25

1

16

Small-scale

0.501

High

240071

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

1

High-throughput

0.489

High

733317

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

933007

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

1

High-throughput

0.489

High

272010

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

536830

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

560342

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

573405

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

580955

RAC2
Ras-related C3 botulinum toxin substrate 2

1

2

High-throughput

0.479

High

774236

BASI
Basigin

1

2

High-throughput

0.479

High

901749

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

932988

RAB14
Ras-related protein Rab-14

1

2

High-throughput

0.479

High

932989

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

933000

TP4A2
Protein tyrosine phosphatase type IVA 2

1

1

Small-scale

0.479

High

933026

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

933052

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

1

High-throughput

0.479

High

933071

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

164293

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

385593

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

390502

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

400538

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

519876

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

565254

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

599181

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

606498

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

698522

CALX
Calnexin

1

0

High-throughput

0.458

High

791217

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

872113

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

897182

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

932997

ITK
Tyrosine-protein kinase ITK/TSK

1

0

High-throughput

0.458

High

933005

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

933008

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

933014

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

933032

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

933039

TM171
Transmembrane protein 171

1

0

High-throughput

0.458

High

933066

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

932986

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.457

High

72905

B1AJQ6
Syntaxin 12

1

20

High-throughput

0.445

High

341922

CEP43
Centrosomal protein 43

1

1

High-throughput

0.445

High

529421

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

932984

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.445

High

933021

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.445

High

933022

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.445

High

933035

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.445

High

933074

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.445

High

933057

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.439

High

105641

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

166282

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

2

High-throughput

0.437

High

633898

ATP4A
Potassium-transporting ATPase alpha chain 1

1

1

Small-scale

0.437

High

710143

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.437

High

932993

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

933023

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

841120

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

932994

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

933006

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.426

High

933017

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

933018

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

933030

S15A4
Solute carrier family 15 member 4

1

0

High-throughput

0.426

High

933036

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

0

High-throughput

0.426

High

933053

S12A5
Solute carrier family 12 member 5

1

0

High-throughput

0.426

High

109560

G5E9T8
Golgi SNAP receptor complex member 1

1

5

High-throughput

0.407

High

116706

I1VE18
SEC22 vesicle trafficking protein B

1

8

High-throughput

0.407

High

330091

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.407

High

779699

MOT8
Monocarboxylate transporter 8

1

1

High-throughput

0.407

High

695034

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.305

High

932985

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

212060

B4GT5
Beta-1,4-galactosyltransferase 5

1

0

High-throughput

0.279

Low

932992

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.279

Low

932998

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.279

Low

933029

TM192
Transmembrane protein 192

1

0

High-throughput

0.279

Low

933031

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.279

Low

933042

YIPF5
Protein YIPF5

1

0

High-throughput

0.279

Low

933054

LIME1
Lck-interacting transmembrane adapter 1

1

0

High-throughput

0.279

Low

933059

SAYS1
SAYSvFN domain-containing protein 1

1

0

High-throughput

0.279

Low

933070

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.279

Low

933072

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

933075

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

218008

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

568388

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

933011

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

933047

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

933063

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

261141

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

932995

TAGL
Transgelin

1

0

High-throughput

0.232

Low

933044

SYMM
Methionine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

933045

FACOS
FANCD2 opposite strand protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025