HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: Q5SRQ6 (Q5SRQ6)
Casein kinase II subunit beta (CK II beta)
Gene: CSNK2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CK_II_beta~Pkinase
Common GO terms	GO:0005956 - protein kinase CK2 complex GO:0016301 - kinase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 234
+	Bt
		931577 CSK21_BOVIN (1-391): 2.89e-136: 396: 100.00		CSK2B_BOVIN (20-234): 1.2e-140: 393: 100.00
+	Hs
		931581 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CSK2B_HUMAN (20-234): 1.2e-140: 393: 100.00
+	Mm
		931967 CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72		CSK2B_MOUSE (20-234): 1.2e-140: 393: 100.00
+	Hs
		931748 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		CSK2B_HUMAN (20-234): 1.2e-140: 393: 100.00
+	Dm
		437047 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		CSK2B_DROME (20-234): 3.36e-136: 383: 88.37
+	Hs
		586675 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		CSK2B_HUMAN (20-234): 1.2e-140: 393: 100.00
+	Hs
		835646 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		CSK2B_HUMAN (20-234): 1.2e-140: 393: 100.00
+	Ce
		576085 CSK2A_CAEEL (4-333): 1.11e-126: 370: 83.33		CSK2B_CAEEL (20-216): 4.2e-123: 350: 82.23
+	Dm
		332363 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		CSK2C_DROME (20-218): 6.48e-111: 319: 65.33
+	Sc
		584733 CSK22_YEAST (2-326): 1.7e-120: 354: 59.51		CSK2C_YEAST (28-227): 3.28e-106: 308: 46.54
+	Sp
		771119 CSK2A_SCHPO (2-325): 1.07e-118: 349: 66.05		CSK2B_SCHPO (28-233): 9.4e-108: 311: 55.34
+	Dm
		437069 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		SSL_DROME (25-215): 1.95e-94: 277: 48.17
+	Sc
		550033 CSK21_YEAST (1-329): 6.88e-113: 336: 54.32		CSK2C_YEAST (28-227): 3.28e-106: 308: 46.54
+	Sp
		292870 CSK2A_SCHPO (2-325): 1.07e-118: 349: 66.05		CSK2C_SCHPO (7-217): 1.04e-96: 284: 49.77
+	Sc
		584757 CSK22_YEAST (2-326): 1.7e-120: 354: 59.51		CSK2B_YEAST (11-215): 2.8e-88: 263: 39.50
+	Dm
		437083 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		STEL8_DROME (28-196): 5.44e-76: 228: 40.24
+	Sc
		550068 CSK21_YEAST (1-329): 6.88e-113: 336: 54.32		CSK2B_YEAST (11-215): 2.8e-88: 263: 39.50
+	Sc
		691047 HOG1_YEAST (39-323): 2.35e-40: 150: 33.56		CSK2C_YEAST (28-227): 3.28e-106: 308: 46.54