Protein: BI1
Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6)

Gene: BI1, TMBIM6
Organism: Homo sapiens
Interactions: 140
UniProt ID: P55061

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002638 - negative regulation of immunoglobulin production
GO:0005262 - calcium channel activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

934264

RN185
E3 ubiquitin-protein ligase RNF185

5

3

High-throughput

0.717

High

934211

ODFP4
Outer dense fiber protein 4

4

0

High-throughput

0.669

High

934272

SERC2
Serine incorporator 2

3

1

High-throughput

0.667

High

934285

SG196
Protein O-mannose kinase

3

1

High-throughput

0.667

High

934251

SPP2B
Signal peptide peptidase-like 2B

3

3

High-throughput

0.662

High

934293

SCN3B
Sodium channel regulatory subunit beta-3

3

2

High-throughput

0.647

High

934292

CLC5A
C-type lectin domain family 5 member A

3

0

High-throughput

0.638

High

934241

K2013
Uncharacterized protein KIAA2013

3

0

High-throughput

0.634

High

320442

TM63A
Mechanosensitive cation channel TMEM63A

2

1

High-throughput

0.628

High

522066

BCL2
Apoptosis regulator Bcl-2

2

4

Small-scale

0.611

High

549755

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.606

High

702754

5HT2C
5-hydroxytryptamine receptor 2C

2

4

High-throughput

0.606

High

722427

CTR1
High affinity cationic amino acid transporter 1

2

1

High-throughput

0.606

High

770839

OPRM
Mu-type opioid receptor

2

4

High-throughput

0.606

High

783002

CXA5
Gap junction alpha-5 protein

2

2

High-throughput

0.606

High

870702

CXA8
Gap junction alpha-8 protein

2

2

High-throughput

0.606

High

873889

KCNC1
Voltage-gated potassium channel KCNC1

2

1

High-throughput

0.606

High

934207

FXYD3
FXYD domain-containing ion transport regulator 3

2

1

High-throughput

0.606

High

934209

KCA10
Potassium voltage-gated channel subfamily A member 10

2

2

High-throughput

0.606

High

934214

F209A
Protein FAM209A

2

1

High-throughput

0.606

High

934217

MF14B
Hippocampus abundant transcript-like protein 1

2

1

High-throughput

0.606

High

934224

CLM9
CMRF35-like molecule 9

2

1

High-throughput

0.606

High

934235

PAQR2
Adiponectin receptor protein 2

2

4

High-throughput

0.606

High

934240

PIANP
PILR alpha-associated neural protein

2

1

High-throughput

0.606

High

934244

EMC5
ER membrane protein complex subunit 5

2

2

High-throughput

0.606

High

934254

GP151
G-protein coupled receptor 151

2

3

High-throughput

0.606

High

934255

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.606

High

934259

ESAM
Endothelial cell-selective adhesion molecule

2

1

High-throughput

0.606

High

934260

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

3

High-throughput

0.606

High

934287

AT131
Endoplasmic reticulum transmembrane helix translocase

2

2

High-throughput

0.606

High

934290

CXB4
Gap junction beta-4 protein

2

2

High-throughput

0.606

High

934299

TMX2
Thioredoxin-related transmembrane protein 2

2

1

High-throughput

0.606

High

934303

S12A7
Solute carrier family 12 member 7

2

2

High-throughput

0.606

High

934279

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

0

High-throughput

0.602

High

844998

EAA3
Excitatory amino acid transporter 3

2

1

High-throughput

0.601

High

705856

DHI1
11-beta-hydroxysteroid dehydrogenase 1

2

0

High-throughput

0.585

High

934267

RN170
E3 ubiquitin-protein ligase RNF170

2

0

High-throughput

0.585

High

132458

CDC7
Cell division cycle 7-related protein kinase

2

0

High-throughput

0.580

High

275828

UDB11
UDP-glucuronosyltransferase 2B11

2

0

High-throughput

0.580

High

296943

SOAT2
Sterol O-acyltransferase 2

2

0

High-throughput

0.580

High

388174

GLPA
Glycophorin-A

2

0

High-throughput

0.580

High

580747

PVR
Poliovirus receptor

2

0

High-throughput

0.580

High

716172

ERP29
Endoplasmic reticulum resident protein 29

2

0

High-throughput

0.580

High

858576

IEX1
Radiation-inducible immediate-early gene IEX-1

2

0

High-throughput

0.580

High

934204

TNR17
Tumor necrosis factor receptor superfamily member 17

2

0

High-throughput

0.580

High

934208

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

934219

STEAL
STEAP family member 1B

2

0

High-throughput

0.580

High

934228

RGMC
Hemojuvelin

2

0

High-throughput

0.580

High

934233

SYT9
Synaptotagmin-9

2

0

High-throughput

0.580

High

934237

TRML1
Trem-like transcript 1 protein

2

0

High-throughput

0.580

High

934238

GPHB5
Glycoprotein hormone beta-5

2

0

High-throughput

0.580

High

934245

TEX29
Testis-expressed protein 29

2

0

High-throughput

0.580

High

934246

CLD22
Claudin-22

2

0

High-throughput

0.580

High

934252

C99L2
CD99 antigen-like protein 2

2

0

High-throughput

0.580

High

934257

LRC59
Leucine-rich repeat-containing protein 59

2

0

High-throughput

0.580

High

934261

SLAF6
SLAM family member 6

2

0

High-throughput

0.580

High

934265

S41A3
Solute carrier family 41 member 3

2

0

High-throughput

0.580

High

934266

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.580

High

934275

REEP2
Receptor expression-enhancing protein 2

2

0

High-throughput

0.580

High

934276

HERP2
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

2

0

High-throughput

0.580

High

934289

MANBL
Protein MANBAL

2

0

High-throughput

0.580

High

934291

RHBL2
Rhomboid-related protein 2

2

0

High-throughput

0.580

High

934300

SIT1
Signaling threshold-regulating transmembrane adapter 1

2

0

High-throughput

0.580

High

934305

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

2

0

High-throughput

0.580

High

934242

LYPD1
Ly6/PLAUR domain-containing protein 1

2

0

High-throughput

0.576

High

934280

OSBL8
Oxysterol-binding protein-related protein 8

2

0

High-throughput

0.576

High

892151

GRAK
Granzyme K

2

1

High-throughput

0.553

High

934269

JSPR1
Junctional sarcoplasmic reticulum protein 1

2

1

High-throughput

0.553

High

165921

FFAR1
Free fatty acid receptor 1

1

8

High-throughput

0.536

High

226317

SNG1
Synaptogyrin-1

1

1

High-throughput

0.536

High

669186

EDNRA
Endothelin-1 receptor

1

5

High-throughput

0.536

High

709260

AA2BR
Adenosine receptor A2b

1

4

High-throughput

0.536

High

732964

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

4

High-throughput

0.536

High

934286

GPR35
G-protein coupled receptor 35

1

5

High-throughput

0.536

High

934258

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

0

High-throughput

0.518

High

193403

GPR42
G-protein coupled receptor 42

1

8

High-throughput

0.515

High

902917

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.513

High

934205

ACHD
Acetylcholine receptor subunit delta

1

0

High-throughput

0.513

High

934206

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.513

High

934210

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

934221

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.513

High

934231

TRPM8
Transient receptor potential cation channel subfamily M member 8

1

0

High-throughput

0.513

High

934232

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

934239

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.513

High

934249

I17RC
Interleukin-17 receptor C

1

0

High-throughput

0.513

High

934262

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.513

High

934271

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.513

High

934282

CHST8
Carbohydrate sulfotransferase 8

1

0

High-throughput

0.513

High

934302

PCDA8
Protocadherin alpha-8

1

0

High-throughput

0.513

High

846048

GLP1R
Glucagon-like peptide 1 receptor

1

4

Small-scale

0.481

High

934270

FER3L
Fer3-like protein

1

2

High-throughput

0.481

High

258258

TRI13
E3 ubiquitin-protein ligase TRIM13

1

3

High-throughput

0.479

High

934226

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

934273

RNF5
E3 ubiquitin-protein ligase RNF5

1

3

High-throughput

0.479

High

934283

P63
Tumor protein 63

1

1

Small-scale

0.479

High

934294

BFAR
Bifunctional apoptosis regulator

1

1

Small-scale

0.479

High

934301

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

47447

A0A7P0TAB9
COBL-like 1, isoform CRA_d

1

1

High-throughput

0.470

High

934215

TMM31
Transmembrane protein 31

1

0

High-throughput

0.460

High

934263

CERS2
Ceramide synthase 2

1

0

High-throughput

0.460

High

241208

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

887402

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.458

High

934216

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

0

High-throughput

0.458

High

934218

DESI1
Desumoylating isopeptidase 1

1

0

Small-scale

0.458

High

934268

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

934298

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

565588

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.445

High

628352

CD33
Myeloid cell surface antigen CD33

1

2

High-throughput

0.445

High

934203

S35A2
UDP-galactose translocator

1

6

High-throughput

0.445

High

934227

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

1

High-throughput

0.445

High

934230

NIPA1
Magnesium transporter NIPA1

1

2

High-throughput

0.445

High

934236

S22AG
Solute carrier family 22 member 16

1

5

High-throughput

0.445

High

934243

S35F6
Solute carrier family 35 member F6

1

6

High-throughput

0.445

High

934250

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.445

High

934253

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.445

High

934274

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

2

High-throughput

0.445

High

934281

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.445

High

934288

GPC5C
G-protein coupled receptor family C group 5 member C

1

3

High-throughput

0.445

High

934213

COBL1
Cordon-bleu protein-like 1

1

2

High-throughput

0.439

High

339257

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.426

High

635840

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

934220

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

0

High-throughput

0.426

High

934225

MFSD6
Major facilitator superfamily domain-containing protein 6

1

0

High-throughput

0.426

High

934234

OSTA
Organic solute transporter subunit alpha

1

0

High-throughput

0.426

High

934248

NLS1
Sodium-dependent lysophosphatidylcholine symporter 1

1

0

High-throughput

0.426

High

934296

S23A2
Solute carrier family 23 member 2

1

0

High-throughput

0.426

High

934297

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.426

High

934304

5MP1
eIF5-mimic protein 1

1

0

High-throughput

0.426

High

934229

S35D2
Nucleotide sugar transporter SLC35D2

1

1

High-throughput

0.407

High

934222

CE046
Uncharacterized protein C5orf46

2

0

High-throughput

0.324

High

934223

PI16
Peptidase inhibitor 16

2

0

High-throughput

0.316

High

934277

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

2

0

High-throughput

0.316

High

934278

FGFP2
Fibroblast growth factor-binding protein 2

2

0

High-throughput

0.316

High

934284

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

590368

COX7C
Cytochrome c oxidase subunit 7C, mitochondrial

1

0

High-throughput

0.279

Low

700780

DMB
HLA class II histocompatibility antigen, DM beta chain

1

0

High-throughput

0.279

Low

934212

MPPE1
Metallophosphoesterase 1

1

0

High-throughput

0.279

Low

934247

MUT7
Exonuclease mut-7 homolog

1

0

High-throughput

0.279

Low

934256

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

0

High-throughput

0.279

Low

934295

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025