HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	26527279, 29568061, 20504901, 20080577
Identification Methods	biochemical, proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 4128
+	Hs
		944182 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		828190 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		935425 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		1086363 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		952722 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		1157244 H3C_HUMAN (1-136): 5.49e-58: 177: 93.38		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Sc
		715229 H3_YEAST (1-136): 1.16e-55: 172: 88.97		TOR1_YEAST (2759-4127): 0: 677: 15.92
+	Hs
		934726 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42
+	Sc
		755442 H3_YEAST (1-136): 1.16e-55: 172: 88.97		TRA1_YEAST (2924-4127): 1.79e-115: 416: 14.57