Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: NPL4 (Q8TAT6)
Nuclear protein localization protein 4 homolog (Protein NPL4)
Gene: NPLOC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.992

The method score is based on:

Property Details
Experiments 26389662, 28320958, 30335548, 31623962, 18586029, 35389758, 18775313, 26549226, 27226613, 27913212, 27762274, 29599191, 29540532, 28443643, 30344098, 33961781, 34262183, 34739333, 35271311, 17872946 and 9 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, x-ray crystallography, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach, cross-linking study and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~NPL4, AAA~zf-NPL4, CDC48_2~UN_NPL4, CDC48_N~UN_NPL4
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 6 others

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Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 806
Hs

1 608
+ Mm
+ Rn
+ Xl
+ Dm
+ Sc
+ Sp

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Last updated: 11Aug2025