HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 128
+	Hs
		469993 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Mm
		470229 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		H2AZ_MOUSE (1-127): 3.62e-60: 182: 98.43
+	Hs
		1086191 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00
+	Hs
		470036 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		935141 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1A_HUMAN (5-125): 2.64e-55: 170: 62.30
+	Mm
		935458 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		Q8CGP4_MOUSE (5-128): 6.15e-55: 169: 60.00
+	Hs
		934815 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		934946 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		935170 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1J_HUMAN (5-125): 1.65e-54: 168: 62.30
+	Hs
		1086165 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		1086203 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		391649 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		470336 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1_HUMAN (5-125): 1.18e-53: 166: 62.30
+	Hs
		555411 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81
+	Hs
		934877 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		1086182 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12
+	Hs
		1086192 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A3_HUMAN (5-125): 8.16e-54: 166: 63.12
+	Hs
		391723 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		470399 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A1_HUMAN (5-125): 1.18e-53: 166: 62.30
+	Hs
		555485 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81