HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: DNM3A (Q9Y6K1)
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)
Gene: DNMT3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.941

Property	Details
Experiments	25281560, 26912663, 34079125, 36089195, 20223770, 19834512
Identification Methods	proximity labelling technology, unspecified method, pull down, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 912
+	Hs
		952734 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		DNM3A_HUMAN (1-912): 0: 1626: 100.00
+	Mm
		291727 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		DNM3A_MOUSE (4-912): 0: 1618: 96.26
+	Hs
		828439 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		DNM3A_HUMAN (1-912): 0: 1626: 100.00
+	Hs
		935328 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		DNM3B_HUMAN (151-911): 0: 1277: 53.07
+	Hs
		952687 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		DNM3L_HUMAN (476-815): 1.32e-179: 525: 40.18
+	Hs
		1174681 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		DNM3L_HUMAN (476-815): 1.32e-179: 525: 40.18
+	Hs
		935132 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PWP2A_HUMAN (286-377): 1.77e-27: 121: 31.58
+	Hs
		952557 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PWP2A_HUMAN (286-377): 1.77e-27: 121: 31.58