HitPredict

Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 18246070
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0032991 - protein-containing complex
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 530
Mm

1 656
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024