HitPredict

Interactor 1: NFIX (P70257)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Interactor 2: Q8VD35 (Q8VD35)
Orthodenticle homeobox 2 (Otx2 protein)
Gene: Otx2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26426291
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Mm			1 289
+	Hs
		620155 NFIX_HUMAN (1-488): 1.17e-162: 471: 99.18		PAX7_HUMAN (6-255): 7.52e-35: 133: 25.10
+	Hs
		641412 NFIX_HUMAN (1-488): 1.17e-162: 471: 99.18		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		197703 NFIA_HUMAN (1-487): 2.65e-122: 368: 66.27		CRX_HUMAN (1-289): 5.69e-41: 145: 46.91
+	Hs
		197649 NFIC_HUMAN (3-487): 7.99e-122: 367: 57.46		CRX_HUMAN (1-289): 5.69e-41: 145: 46.91
+	Hs
		620148 NFIA_HUMAN (1-487): 2.65e-122: 368: 66.27		PAX7_HUMAN (6-255): 7.52e-35: 133: 25.10
+	Hs
		443128 NFIC_HUMAN (3-487): 7.99e-122: 367: 57.46		PAX7_HUMAN (6-255): 7.52e-35: 133: 25.10
+	Hs
		1018276 NFIA_HUMAN (1-487): 2.65e-122: 368: 66.27		LHX3_HUMAN (39-264): 6.99e-35: 131: 21.46
+	Hs
		641392 NFIA_HUMAN (1-487): 2.65e-122: 368: 66.27		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		443132 NFIC_HUMAN (3-487): 7.99e-122: 367: 57.46		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		443262 NFIC_HUMAN (3-487): 7.99e-122: 367: 57.46		LHX3_HUMAN (39-264): 6.99e-35: 131: 21.46
+	Hs
		135075 NFIB_HUMAN (1-419): 1.01e-111: 338: 58.45		PAX7_HUMAN (6-255): 7.52e-35: 133: 25.10
+	Hs
		135079 NFIB_HUMAN (1-419): 1.01e-111: 338: 58.45		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		135170 NFIB_HUMAN (1-419): 1.01e-111: 338: 58.45		LHX3_HUMAN (39-264): 6.99e-35: 131: 21.46
+	Hs
		135094 NFIB_HUMAN (1-419): 1.01e-111: 338: 58.45		LHX1_HUMAN (3-237): 1.5e-33: 128: 22.57
+	Hs
		882126 NFIA_HUMAN (1-487): 2.65e-122: 368: 66.27		GSC_HUMAN (36-128): 2.04e-16: 79: 46.81
+	Hs
		443160 NFIC_HUMAN (3-487): 7.99e-122: 367: 57.46		GSC_HUMAN (36-128): 2.04e-16: 79: 46.81
+	Hs
		197766 KMT2C_HUMAN (147-477): 2.34e-09: 62.2: 11.59		CRX_HUMAN (1-289): 5.69e-41: 145: 46.91
+	Hs
		201848 SYNJ1_HUMAN (207-486): 1.48e-10: 66.1: 13.10		HXA2_HUMAN (31-276): 1.97e-35: 132: 20.73
+	Hs
		203210 SYNJ1_HUMAN (207-486): 1.48e-10: 66.1: 13.10		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		641616 CABIN_HUMAN (174-429): 7.66e-10: 63.8: 8.98		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39