HitPredict

Interactor 1: SMAD1 (P70340)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (Dwarfin-A) (Dwf-A) (Mothers-against-DPP-related 1) (Mad-related protein 1) (mMad1) (SMAD family member 1) (SMAD 1) (Smad1)
Gene: SMAD1

Interactor 2: ZFY16 (Q80U44)
Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal-associated FYVE domain protein)
Gene: Zfyve16

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17356069
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 465 Mm			1 1528
+	Hs
		1035486 SMAD4_HUMAN (8-454): 1.16e-150: 441: 33.15		ZFY16_HUMAN (1-1526): 0: 1711: 72.82
+	Hs
		313526 SMAD3_HUMAN (3-465): 0: 554: 59.44		ZFYV9_HUMAN (1-1526): 0: 1420: 31.60
+	Hs
		313541 SMAD2_HUMAN (3-465): 0: 537: 55.14		ZFYV9_HUMAN (1-1526): 0: 1420: 31.60
+	Hs
		313534 SMAD4_HUMAN (8-454): 1.16e-150: 441: 33.15		ZFYV9_HUMAN (1-1526): 0: 1420: 31.60
+	Hs
		950306 SMAD3_HUMAN (3-465): 0: 554: 59.44		MTMR4_HUMAN (203-814): 2.09e-100: 352: 15.24
+	Hs
		1078687 SMAD2_HUMAN (3-465): 0: 537: 55.14		MTMR4_HUMAN (203-814): 2.09e-100: 352: 15.24
+	Hs
		160011 SMAD1_HUMAN (1-465): 0: 653: 99.14		HGS_HUMAN (592-992): 3.49e-60: 224: 17.96
+	Hs
		1035573 SMAD4_HUMAN (8-454): 1.16e-150: 441: 33.15		FYCO1_HUMAN (103-995): 2.08e-119: 412: 14.65
+	Hs
		160166 SMAD5_HUMAN (2-465): 0: 618: 89.25		HGS_HUMAN (592-992): 3.49e-60: 224: 17.96
+	Hs
		159959 SMAD3_HUMAN (3-465): 0: 554: 59.44		HGS_HUMAN (592-992): 3.49e-60: 224: 17.96
+	Hs
		160010 SMAD2_HUMAN (3-465): 0: 537: 55.14		HGS_HUMAN (592-992): 3.49e-60: 224: 17.96
+	Hs
		159987 SMAD4_HUMAN (8-454): 1.16e-150: 441: 33.15		HGS_HUMAN (592-992): 3.49e-60: 224: 17.96