HitPredict - High confidence protein-protein interactions

Interactor 1: TANK (P70347)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK

Interactor 2: TANK (P70347)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	10490605, 17568778
Identification Methods	anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004843 - cysteine-type deubiquitinase activity GO:0005829 - cytosol GO:0006974 - DNA damage response GO:0007249 - canonical NF-kappaB signal transduction GO:0010804 - negative regulation of tumor necrosis factor-mediated signaling pathway and 13 others more... GO:0031625 - ubiquitin protein ligase binding GO:0032481 - positive regulation of type I interferon production GO:0032991 - protein-containing complex GO:0035800 - deubiquitinase activator activity GO:0043124 - negative regulation of canonical NF-kappaB signal transduction GO:0046872 - metal ion binding GO:0060090 - molecular adaptor activity GO:0071347 - cellular response to interleukin-1 GO:0071356 - cellular response to tumor necrosis factor GO:0071479 - cellular response to ionizing radiation GO:0140678 - molecular function inhibitor activity GO:1903003 - positive regulation of protein deubiquitination GO:2000158 - positive regulation of ubiquitin-specific protease activity
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	448
Mm

1	448

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024