Protein: ELL2
RNA polymerase II elongation factor ELL2

Gene: ELL2
Organism: Homo sapiens
Interactions: 55
UniProt ID: O00472

Gene Ontology (top 5):
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
GO:0008023 - transcription elongation factor complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

137342

EAF1
ELL-associated factor 1

8

5

Small-scale

0.968

High

137345

AFF4
AF4/FMR2 family member 4

7

16

Small-scale

0.966

High

137323

AFF1
AF4/FMR2 family member 1

3

18

Small-scale

0.861

High

137341

EAF2
ELL-associated factor 2

2

5

Small-scale

0.789

High

137322

CDK9
Cyclin-dependent kinase 9

5

7

Small-scale

0.709

High

137328

ENL
Protein ENL

4

15

Small-scale

0.699

High

137319

AF9
Protein AF-9

4

12

Small-scale

0.694

High

137320

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

2

High-throughput

0.628

High

48871

MED19
Mediator of RNA polymerase II transcription subunit 19

2

1

High-throughput

0.601

High

137306

MED26
Mediator of RNA polymerase II transcription subunit 26

2

3

High-throughput

0.601

High

137347

ICE1
Little elongation complex subunit 1

2

2

Small-scale

0.601

High

137338

Q8TAX5
AFF4 protein

1

7

High-throughput

0.594

High

137301

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

137335

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

1

Small-scale

0.575

High

137302

CCNT1
Cyclin-T1

1

11

High-throughput

0.536

High

137303

CCNT2
Cyclin-T2

1

11

High-throughput

0.536

High

137333

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.536

High

137304

PR40A
Pre-mRNA-processing factor 40 homolog A

1

11

High-throughput

0.515

High

137326

RAN
GTP-binding nuclear protein Ran

1

10

High-throughput

0.515

High

137346

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

137299

CSKP
Peripheral plasma membrane protein CASK

1

7

High-throughput

0.494

High

137324

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

137325

CASP6
Caspase-6

1

0

High-throughput

0.493

High

137337

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.493

High

137305

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.489

High

137307

B3A2
Anion exchange protein 2

1

2

High-throughput

0.489

High

137329

EFR3A
Protein EFR3 homolog A

1

2

High-throughput

0.489

High

137334

NBEL2
Neurobeachin-like protein 2

1

4

High-throughput

0.489

High

137300

RNF13
E3 ubiquitin-protein ligase RNF13

1

4

High-throughput

0.479

High

137315

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

2

High-throughput

0.479

High

137327

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

137331

IRF4
Interferon regulatory factor 4

1

1

Small-scale

0.479

High

137310

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.470

High

137311

FLNA
Filamin-A

1

6

High-throughput

0.470

High

137312

FGFR3
Fibroblast growth factor receptor 3

1

14

High-throughput

0.470

High

137316

SYUA
Alpha-synuclein

1

2

High-throughput

0.470

High

137340

APBB2
Amyloid beta precursor protein binding family B member 2

1

1

High-throughput

0.470

High

137348

SHLB1
Endophilin-B1

1

7

High-throughput

0.470

High

137318

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.458

High

107420

F8W8I6
Cytotoxic granule associated RNA binding protein TIA1

1

2

High-throughput

0.445

High

137332

ICE2
Little elongation complex subunit 2

1

2

Small-scale

0.445

High

137343

MED10
Mediator of RNA polymerase II transcription subunit 10

1

1

High-throughput

0.445

High

137344

RN181
E3 ubiquitin-protein ligase RNF181

1

2

Small-scale

0.439

High

48432

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.437

High

116436

H7BXI1
Extended synaptotagmin-2

1

6

High-throughput

0.407

High

137336

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.316

High

137339

NICA
Nicastrin

1

0

High-throughput

0.279

Low

137349

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low

137308

GELS
Gelsolin

1

0

High-throughput

0.268

Low

137309

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.268

Low

137313

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

137314

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.268

Low

137321

PSN2
Presenilin-2

1

0

High-throughput

0.268

Low

137330

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

137317

AQP2
Aquaporin-2

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025