Interactor 1: RAD50 (P70388)
DNA repair protein RAD50 (mRad50) (EC 3.6.-.-)
Gene: RAD50

Interactor 2: MRE11 (Q61216)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) (MmMRE11A)
Gene: MRE11

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 18854157
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_23~Metallophos, AAA_23~Mre11_DNA_bind, Metallophos~SbcC_Walker_B
Common GO terms GO:0000729 - DNA double-strand break processing
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0000794 - condensed nuclear chromosome
GO:0005634 - nucleus
and 14 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1312
Mm

1 706
+ Hs
+ At
+ Sc
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024