HitPredict

Interactor 1: NHRF1 (P70441)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: Nherf1

Interactor 2: PODXL (Q9R0M4)
Podocalyxin (Podocalyxin-like protein 1) (PC) (PCLP-1)
Gene: PODXL

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16410385
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001726 - ruffle GO:0005737 - cytoplasm GO:0016324 - apical plasma membrane GO:0030175 - filopodium GO:0031528 - microvillus membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 355 Mm			1 503
+	Hs
		134424 NHRF1_HUMAN (1-355): 1.54e-75: 238: 83.89		PODXL_HUMAN (13-503): 9.39e-55: 194: 40.65
+	Hs
		153955 NHRF1_HUMAN (1-355): 1.54e-75: 238: 83.89		PDXL2_HUMAN (17-503): 1.96e-31: 129: 16.73
+	Oc
		1100192 NHRF2_RABIT (4-169): 1.38e-21: 95.4: 38.92		PODXL_RABIT (4-503): 1.81e-55: 196: 42.91
+	Hs
		134469 NHRF2_HUMAN (4-182): 6.81e-21: 93.9: 36.61		PODXL_HUMAN (13-503): 9.39e-55: 194: 40.65
+	Hs
		1075466 NHRF2_HUMAN (4-182): 6.81e-21: 93.9: 36.61		PDXL2_HUMAN (17-503): 1.96e-31: 129: 16.73
+	Mm
		57254 A2AKD7_MOUSE (2-345): 1.6e-41: 153: 15.18		NACAM_MOUSE (2-413): 7.56e-09: 60.5: 9.88
+	Mm
		88458 DLG4_MOUSE (88-230): 4.66e-12: 69.3: 21.33		D3Z656_MOUSE (1-409): 3.31e-23: 105: 9.15
+	Hs
		624948 MAGI2_HUMAN (2-151): 3.62e-18: 88.1: 20.48		RPB1_HUMAN (40-226): 4.89e-09: 61.2: 16.49
+	Mm
		1143433 DLG4_MOUSE (88-230): 4.66e-12: 69.3: 21.33		SYNJ1_MOUSE (12-353): 6.92e-09: 60.9: 8.89