Interactor 1: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Interactor 2: TCAM1 (Q80UF7)
TIR domain-containing adapter molecule 1 (TICAM-1) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (TIR domain-containing adapter protein inducing IFN-beta)
Gene: Ticam1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 17327220
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0031663 - lipopolysaccharide-mediated signaling pathway
GO:0032481 - positive regulation of type I interferon production
GO:0032496 - response to lipopolysaccharide
and 7 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 419
Mm

1 732
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024