Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
XIAP
E3 ubiquitin-protein ligase XIAP |
35 |
20 |
Small-scale |
0.994 | High |
|
|
CASP9
Caspase-9 |
9 |
17 |
Small-scale |
0.968 | High |
|
|
CASP8
Caspase-8 |
8 |
17 |
Small-scale |
0.959 | High |
|
|
BIRC2
Baculoviral IAP repeat-containing protein 2 |
5 |
20 |
Small-scale |
0.924 | High |
|
|
BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 |
4 |
20 |
Small-scale |
0.909 | High |
|
|
BIRC5
Baculoviral IAP repeat-containing protein 5 |
3 |
20 |
Small-scale |
0.853 | High |
|
|
BIRC7
Baculoviral IAP repeat-containing protein 7 |
3 |
20 |
Small-scale |
0.834 | High |
|
|
CASP6
Caspase-6 |
2 |
18 |
Small-scale |
0.825 | High |
|
|
BIRC3
Baculoviral IAP repeat-containing protein 3 |
2 |
20 |
Small-scale |
0.789 | High |
|
|
CFLAR
CASP8 and FADD-like apoptosis regulator |
2 |
17 |
Small-scale |
0.783 | High |
|
|
CASP2
Caspase-2 |
2 |
17 |
Small-scale |
0.778 | High |
|
|
CASPA
Caspase-10 |
2 |
17 |
Small-scale |
0.755 | High |
|
|
PARP1
Poly [ADP-ribose] polymerase 1 |
9 |
9 |
Small-scale |
0.754 | High |
|
|
GRAB
Granzyme B |
11 |
12 |
Small-scale |
0.747 | High |
|
|
MDM2
E3 ubiquitin-protein ligase Mdm2 |
4 |
1 |
Small-scale |
0.683 | High |
|
|
CRYAB
Alpha-crystallin B chain |
3 |
10 |
Small-scale |
0.664 | High |
|
|
CDN1A
Cyclin-dependent kinase inhibitor 1 |
4 |
0 |
Small-scale |
0.657 | High |
|
|
TAU
Microtubule-associated protein tau |
3 |
7 |
Small-scale |
0.655 | High |
|
|
TEBP
Prostaglandin E synthase 3 |
3 |
3 |
Small-scale |
0.651 | High |
|
|
CASP7
Caspase-7 |
1 |
18 |
Small-scale |
0.647 | High |
|
|
CASP3
Caspase-3 |
1 |
17 |
Small-scale |
0.646 | High |
|
|
BID
BH3-interacting domain death agonist |
2 |
4 |
Small-scale |
0.625 | High |
|
|
FETA
Alpha-fetoprotein |
2 |
0 |
Small-scale |
0.607 | High |
|
|
THIO
Thioredoxin |
1 |
1 |
Small-scale |
0.604 | High |
|
|
GELS
Gelsolin |
2 |
3 |
Small-scale |
0.602 | High |
|
|
RB
Retinoblastoma-associated protein |
2 |
5 |
Small-scale |
0.602 | High |
|
|
HCLS1
Hematopoietic lineage cell-specific protein |
2 |
5 |
Small-scale |
0.602 | High |
|
|
PRKDC
DNA-dependent protein kinase catalytic subunit |
2 |
2 |
Small-scale |
0.602 | High |
|
|
TRAF3
TNF receptor-associated factor 3 |
2 |
20 |
Small-scale |
0.602 | High |
|
|
PANX1
Pannexin-1 |
2 |
2 |
Small-scale |
0.595 | High |
|
|
A4
Amyloid-beta precursor protein |
2 |
4 |
Small-scale |
0.588 | High |
|
|
DFFA
DNA fragmentation factor subunit alpha |
2 |
3 |
Small-scale |
0.585 | High |
|
|
GDIR1
Rho GDP-dissociation inhibitor 1 |
2 |
8 |
Small-scale |
0.585 | High |
|
|
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 |
2 |
6 |
Small-scale |
0.585 | High |
|
|
CH60
60 kDa heat shock protein, mitochondrial |
2 |
2 |
Small-scale |
0.584 | High |
|
|
SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 |
2 |
0 |
High-throughput |
0.580 | High |
|
|
CASP1
Caspase-1 |
1 |
17 |
Small-scale |
0.575 | High |
|
|
IL18
Interleukin-18 |
1 |
3 |
Small-scale |
0.575 | High |
|
|
NMT2
Glycylpeptide N-tetradecanoyltransferase 2 |
2 |
2 |
Small-scale |
0.571 | High |
|
|
MK14
Mitogen-activated protein kinase 14 |
1 |
11 |
Small-scale |
0.554 | High |
|
|
DCC
Netrin receptor DCC |
1 |
1 |
Small-scale |
0.552 | High |
|
|
A16L1
Autophagy-related protein 16-1 |
2 |
4 |
Small-scale |
0.552 | High |
|
|
ATG4D
Cysteine protease ATG4D |
1 |
1 |
Small-scale |
0.550 | High |
|
|
SOCS5
Suppressor of cytokine signaling 5 |
1 |
3 |
High-throughput |
0.541 | High |
|
|
1433G
14-3-3 protein gamma |
1 |
4 |
High-throughput |
0.541 | High |
|
|
APAF
Apoptotic protease-activating factor 1 |
2 |
5 |
Small-scale |
0.538 | High |
|
|
ARNT
Aryl hydrocarbon receptor nuclear translocator |
1 |
3 |
Small-scale |
0.536 | High |
|
|
PDPK1
3-phosphoinositide-dependent protein kinase 1 |
1 |
6 |
High-throughput |
0.536 | High |
|
|
PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform |
1 |
3 |
Small-scale |
0.536 | High |
|
|
GATA1
Erythroid transcription factor |
1 |
0 |
Small-scale |
0.527 | High |
|
|
GLRX1
Glutaredoxin-1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
GDIR2
Rho GDP-dissociation inhibitor 2 |
1 |
8 |
Small-scale |
0.516 | High |
|
|
RBX1
E3 ubiquitin-protein ligase RBX1 |
1 |
3 |
Small-scale |
0.515 | High |
|
|
WNK3
Serine/threonine-protein kinase WNK3 |
1 |
4 |
Small-scale |
0.515 | High |
|
|
FBW1B
F-box/WD repeat-containing protein 11 |
1 |
4 |
Small-scale |
0.515 | High |
|
|
FBW1A
F-box/WD repeat-containing protein 1A |
1 |
4 |
Small-scale |
0.515 | High |
|
|
HD
Huntingtin |
1 |
4 |
High-throughput |
0.515 | High |
|
|
ATX3
Ataxin-3 |
1 |
2 |
High-throughput |
0.515 | High |
|
|
DCTN1
Dynactin subunit 1 |
1 |
4 |
High-throughput |
0.515 | High |
|
|
MED20
Mediator of RNA polymerase II transcription subunit 20 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
USO1
General vesicular transport factor p115 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
GEMI
Geminin |
1 |
1 |
Small-scale |
0.501 | High |
|
|
SP1
Transcription factor Sp1 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
VIME
Vimentin |
1 |
5 |
Small-scale |
0.501 | High |
|
|
PA24B
Cytosolic phospholipase A2 beta |
1 |
7 |
Small-scale |
0.501 | High |
|
|
BCL2
Apoptosis regulator Bcl-2 |
1 |
8 |
Small-scale |
0.501 | High |
|
|
STAT1
Signal transducer and activator of transcription 1-alpha/beta |
1 |
2 |
Small-scale |
0.501 | High |
|
|
MK08
Mitogen-activated protein kinase 8 |
1 |
11 |
Small-scale |
0.501 | High |
|
|
MK09
Mitogen-activated protein kinase 9 |
1 |
11 |
Small-scale |
0.501 | High |
|
|
TNF10
Tumor necrosis factor ligand superfamily member 10 |
1 |
13 |
Small-scale |
0.501 | High |
|
|
BMX
Cytoplasmic tyrosine-protein kinase BMX |
1 |
2 |
Small-scale |
0.501 | High |
|
|
BLM
RecQ-like DNA helicase BLM |
1 |
5 |
Small-scale |
0.501 | High |
|
|
ZBT16
Zinc finger and BTB domain-containing protein 16 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
SRBP2
Sterol regulatory element-binding protein 2 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
ROCK1
Rho-associated protein kinase 1 |
1 |
4 |
Small-scale |
0.501 | High |
|
|
SPTN1
Spectrin alpha chain, non-erythrocytic 1 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
SRC8
Src substrate cortactin |
1 |
5 |
Small-scale |
0.501 | High |
|
|
BECN1
Beclin-1 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
MDC1
Mediator of DNA damage checkpoint protein 1 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
PKN1
Serine/threonine-protein kinase N1 |
1 |
4 |
Small-scale |
0.501 | High |
|
|
GRAP1
GRIP1-associated protein 1 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
CSN6
COP9 signalosome complex subunit 6 |
1 |
5 |
Small-scale |
0.501 | High |
|
|
RING2
E3 ubiquitin-protein ligase RING2 |
1 |
6 |
Small-scale |
0.501 | High |
|
|
DBNL
Drebrin-like protein |
1 |
2 |
Small-scale |
0.501 | High |
|
|
AKAP8
A-kinase anchor protein 8 |
1 |
0 |
Small-scale |
0.493 | High |
|
|
IF4E
Eukaryotic translation initiation factor 4E |
1 |
0 |
High-throughput |
0.493 | High |
|
|
ERP44
Endoplasmic reticulum resident protein 44 |
1 |
3 |
High-throughput |
0.489 | High |
|
|
AKT1
RAC-alpha serine/threonine-protein kinase |
1 |
4 |
Small-scale |
0.484 | High |
|
|
AKT2
RAC-beta serine/threonine-protein kinase |
1 |
5 |
Small-scale |
0.484 | High |
|
|
PA24A
Cytosolic phospholipase A2 |
1 |
7 |
Small-scale |
0.484 | High |
|
|
AKT3
RAC-gamma serine/threonine-protein kinase |
1 |
4 |
Small-scale |
0.484 | High |
|
|
CALB1
Calbindin |
1 |
0 |
Small-scale |
0.480 | High |
|
|
RU17
U1 small nuclear ribonucleoprotein 70 kDa |
1 |
0 |
Small-scale |
0.480 | High |
|
|
PARG
Poly(ADP-ribose) glycohydrolase |
1 |
0 |
Small-scale |
0.480 | High |
|
|
PRKN
E3 ubiquitin-protein ligase parkin |
1 |
5 |
High-throughput |
0.479 | High |
|
|
P53
Cellular tumor antigen p53 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
HSPB1
Heat shock protein beta-1 |
1 |
10 |
Small-scale |
0.479 | High |
|
|
ENOA
Alpha-enolase |
1 |
1 |
High-throughput |
0.479 | High |
|
|
CDK2
Cyclin-dependent kinase 2 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
RFA3
Replication protein A 14 kDa subunit |
1 |
3 |
High-throughput |
0.479 | High |
|
|
CCNF
Cyclin-F |
1 |
1 |
High-throughput |
0.479 | High |
|
|
UBE2H
Ubiquitin-conjugating enzyme E2 H |
1 |
2 |
High-throughput |
0.479 | High |
|
|
PPIA
Peptidyl-prolyl cis-trans isomerase A |
1 |
1 |
High-throughput |
0.479 | High |
|
|
TIF1B
Transcription intermediary factor 1-beta |
1 |
8 |
High-throughput |
0.479 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
TRI67
Tripartite motif-containing protein 67 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
RBX2
RING-box protein 2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
ZRAN1
Ubiquitin thioesterase ZRANB1 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
OSTP
Osteopontin |
1 |
1 |
Small-scale |
0.471 | High |
|
|
THA11
THAP domain-containing protein 11 |
1 |
0 |
Small-scale |
0.460 | High |
|
|
RFA1
Replication protein A 70 kDa DNA-binding subunit |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CH10
10 kDa heat shock protein, mitochondrial |
1 |
0 |
Small-scale |
0.458 | High |
|
|
HNRPD
Heterogeneous nuclear ribonucleoprotein D0 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
ELAV1
ELAV-like protein 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
NAA40
N-alpha-acetyltransferase 40 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
SERB1
SERPINE1 mRNA-binding protein 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
OTUL
Ubiquitin thioesterase otulin |
1 |
0 |
Small-scale |
0.458 | High |
|
|
HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
1433E
14-3-3 protein epsilon |
1 |
1 |
Small-scale |
0.457 | High |
|
|
IL33
Interleukin-33 |
1 |
2 |
Small-scale |
0.445 | High |
|
|
EGFR
Epidermal growth factor receptor |
1 |
6 |
Small-scale |
0.445 | High |
|
|
TBB5
Tubulin beta chain |
1 |
3 |
High-throughput |
0.445 | High |
|
|
CADH1
Cadherin-1 |
1 |
2 |
Small-scale |
0.445 | High |
|
|
CFTR
Cystic fibrosis transmembrane conductance regulator |
1 |
3 |
High-throughput |
0.445 | High |
|
|
GRAH
Granzyme H |
1 |
12 |
Small-scale |
0.445 | High |
|
|
CD3Z
T-cell surface glycoprotein CD3 zeta chain |
1 |
1 |
Small-scale |
0.445 | High |
|
|
NMT1
Glycylpeptide N-tetradecanoyltransferase 1 |
1 |
2 |
Small-scale |
0.445 | High |
|
|
GRAM
Granzyme M |
1 |
11 |
Small-scale |
0.445 | High |
|
|
NUCB2
Nucleobindin-2 |
1 |
5 |
Small-scale |
0.445 | High |
|
|
PAK2
Serine/threonine-protein kinase PAK 2 |
1 |
6 |
Small-scale |
0.445 | High |
|
|
LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2 |
1 |
2 |
High-throughput |
0.445 | High |
|
|
HDAC7
Histone deacetylase 7 |
1 |
6 |
Small-scale |
0.445 | High |
|
|
CIA2A
Cytosolic iron-sulfur assembly component 2A |
1 |
1 |
High-throughput |
0.445 | High |
|
|
RON
Macrophage-stimulating protein receptor |
1 |
1 |
High-throughput |
0.437 | High |
|
|
RET
Proto-oncogene tyrosine-protein kinase receptor Ret |
1 |
3 |
Small-scale |
0.407 | High |
|
|
KLK2
Kallikrein-2 |
1 |
2 |
High-throughput |
0.407 | High |
|
|
MAVS
Mitochondrial antiviral-signaling protein |
1 |
4 |
Small-scale |
0.407 | High |
|
|
LS14B
Protein LSM14 homolog B |
2 |
0 |
High-throughput |
0.328 | High |
|
|
S35A1
CMP-sialic acid transporter |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
KCA10
Potassium voltage-gated channel subfamily A member 10 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
1 |
0 |
Small-scale |
0.261 | Low |
|
|
GORS1
Golgi reassembly-stacking protein 1 |
1 |
0 |
Small-scale |
0.261 | Low |
|
|
RAMP3
Receptor activity-modifying protein 3 |
1 |
0 |
High-throughput |
0.232 | Low |
|
|
HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 |
1 |
0 |
High-throughput |
0.232 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
