HitPredict

Interactor 1: SCOT1 (P55809)
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase)
Gene: OXCT1

Interactor 2: SCOT1 (P55809)
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase)
Gene: OXCT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

The method score is based on:

Property	Details
Experiments	27499296, 31839598
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CoA_trans~CoA_trans
Common GO terms	GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0007507 - heart development GO:0007584 - response to nutrient GO:0008260 - succinyl-CoA:3-oxo-acid CoA-transferase activity and 10 others more... GO:0009410 - response to xenobiotic stimulus GO:0009725 - response to hormone GO:0014823 - response to activity GO:0035774 - positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0042182 - ketone catabolic process GO:0042594 - response to starvation GO:0045471 - response to ethanol GO:0046952 - ketone body catabolic process GO:0060612 - adipose tissue development GO:1902224 - ketone body metabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	520
Hs

1	520

Service provided by Combinatics, Japan

Last updated: 11Aug2025