HitPredict

Interactor 1: RBM6 (P78332)
RNA-binding protein 6 (Lung cancer antigen NY-LU-12) (Protein G16) (RNA-binding motif protein 6) (RNA-binding protein DEF-3)
Gene: RBM6

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1123 Hs			1 504
+	Hs
		941812 RBM6_HUMAN (1-1123): 0: 807: 100.00		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		958154 RBM10_HUMAN (184-1121): 8.07e-114: 377: 18.70		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		856132 RBM5_HUMAN (417-1123): 5.16e-111: 367: 24.45		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		958100 RBM10_HUMAN (184-1121): 8.07e-114: 377: 18.70		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		958102 RBM10_HUMAN (184-1121): 8.07e-114: 377: 18.70		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		856108 RBM5_HUMAN (417-1123): 5.16e-111: 367: 24.45		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		446840 SNRPA_HUMAN (451-740): 3.38e-13: 73.4: 13.65		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		582421 NUCL_HUMAN (379-743): 8.76e-67: 241: 17.81		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1288258 MINT_HUMAN (162-1117): 2.35e-73: 270: 11.47		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		1302927 MINT_HUMAN (162-1117): 2.35e-73: 270: 11.47		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		1219993 SUGP1_HUMAN (861-1120): 1.81e-52: 197: 14.34		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		582176 NUCL_HUMAN (379-743): 8.76e-67: 241: 17.81		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		903196 PABP4_HUMAN (329-542): 5.81e-29: 126: 11.22		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		516438 PABP1_HUMAN (329-542): 1.32e-28: 124: 10.75		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		446738 SNRPA_HUMAN (451-740): 3.38e-13: 73.4: 13.65		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		196944 SNRPA_HUMAN (451-740): 3.38e-13: 73.4: 13.65		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84