HitPredict

Interactor 1: PITX1 (P78337)
Pituitary homeobox 1 (Hindlimb-expressed homeobox protein backfoot) (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1)
Gene: PITX1

Interactor 2: Q86V38 (Q86V38)
Atrophin 1
Gene: ATN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 314 Hs			1 1191
+	Hs
		869449 PITX1_HUMAN (1-314): 1.88e-63: 204: 100.00		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Hs
		1200908 PITX2_HUMAN (41-312): 2.13e-46: 160: 67.15		Q86V38_HUMAN (1-1191): 9.89e-151: 485: 100.00
+	Hs
		869519 PITX2_HUMAN (41-312): 2.13e-46: 160: 67.15		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Hs
		1200894 LMX1A_HUMAN (46-258): 3.73e-31: 122: 18.94		Q86V38_HUMAN (1-1191): 9.89e-151: 485: 100.00
+	Hs
		641482 PAX6_HUMAN (42-269): 2.26e-38: 142: 24.00		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		203210 PAX6_HUMAN (42-269): 2.26e-38: 142: 24.00		SYNJ1_HUMAN (481-1012): 4.33e-10: 66.4: 12.68
+	Hs
		131694 PAX6_HUMAN (42-269): 2.26e-38: 142: 24.00		BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16
+	Hs
		620175 PAX7_HUMAN (72-314): 1.72e-35: 135: 24.60		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		641583 PAX6_HUMAN (42-269): 2.26e-38: 142: 24.00		CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92
+	Hs
		641457 PAX6_HUMAN (42-269): 2.26e-38: 142: 24.00		SRCAP_HUMAN (20-543): 6.13e-09: 62.7: 15.21
+	Hs
		822650 LHX1_HUMAN (26-305): 3.07e-34: 130: 14.58		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		131691 PAX7_HUMAN (72-314): 1.72e-35: 135: 24.60		BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16
+	Hs
		620215 PAX7_HUMAN (72-314): 1.72e-35: 135: 24.60		CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92
+	Mm
		292012 LMX1B_MOUSE (47-258): 1.06e-30: 121: 22.37		F186A_MOUSE (346-982): 4.14e-13: 76.4: 9.52
+	Hs
		131702 LHX1_HUMAN (26-305): 3.07e-34: 130: 14.58		BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16
+	Hs
		822688 LHX1_HUMAN (26-305): 3.07e-34: 130: 14.58		CHD7_HUMAN (183-895): 1.4e-09: 64.9: 9.92
+	Hs
		201848 HXA2_HUMAN (3-302): 3.29e-31: 121: 17.67		SYNJ1_HUMAN (481-1012): 4.33e-10: 66.4: 12.68
+	Hs
		257570 HXA7_HUMAN (19-161): 3.36e-30: 116: 22.38		ANR17_HUMAN (220-742): 1.51e-10: 68.2: 12.14