Protein: PEX3
Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3)

Gene: PEX3
Organism: Homo sapiens
Interactions: 185
UniProt ID: P56589

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005783 - endoplasmic reticulum
GO:0007031 - peroxisome organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

828347

PEX19
Peroxisomal biogenesis factor 19

24

2

Small-scale

0.769

High

941996

PEX16
Peroxisomal membrane protein PEX16

4

0

Small-scale

0.658

High

701787

ABCD3
ATP-binding cassette sub-family D member 3

2

1

High-throughput

0.611

High

941907

PCBP1
Poly(rC)-binding protein 1

2

1

High-throughput

0.601

High

941980

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

Small-scale

0.576

High

941901

FLOT2
Flotillin-2

2

1

High-throughput

0.571

High

278839

PEX14
Peroxisomal membrane protein PEX14

2

0

Small-scale

0.563

High

941979

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.559

High

771108

APJ
Apelin receptor

2

1

High-throughput

0.549

High

165922

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.536

High

182503

GP182
G-protein coupled receptor 182

1

3

High-throughput

0.536

High

538558

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.536

High

638404

FPR1
fMet-Leu-Phe receptor

1

3

High-throughput

0.536

High

668984

FPR2
N-formyl peptide receptor 2

1

3

High-throughput

0.536

High

941945

AQP3
Aquaporin-3

1

1

High-throughput

0.536

High

941952

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.536

High

941960

CML1
Chemerin-like receptor 1

1

3

High-throughput

0.536

High

49736

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

522068

BCL2
Apoptosis regulator Bcl-2

1

0

High-throughput

0.513

High

844999

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

941911

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

941917

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.513

High

941929

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

941932

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

941933

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

941939

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

941941

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

941967

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.513

High

603217

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.493

High

941927

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

2

High-throughput

0.489

High

941922

PEX26
Peroxisome assembly protein 26

1

0

Small-scale

0.480

High

162179

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.479

High

172627

XPO1
Exportin-1

1

2

High-throughput

0.479

High

184420

SURF4
Surfeit locus protein 4

1

1

High-throughput

0.479

High

192225

YKT6
Synaptobrevin homolog YKT6

1

2

High-throughput

0.479

High

208991

CYB5B
Cytochrome b5 type B

1

2

High-throughput

0.479

High

231691

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.479

High

452216

PDIA1
Protein disulfide-isomerase

1

1

High-throughput

0.479

High

566605

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.479

High

598049

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.479

High

627294

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

2

High-throughput

0.479

High

697817

CALR
Calreticulin

1

1

High-throughput

0.479

High

698529

CALX
Calnexin

1

1

High-throughput

0.479

High

755335

ABCD1
ATP-binding cassette sub-family D member 1

1

1

High-throughput

0.479

High

834407

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

906022

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

1

High-throughput

0.479

High

941891

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

High-throughput

0.479

High

941899

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.479

High

941905

S39AE
Metal cation symporter ZIP14

1

1

High-throughput

0.479

High

941914

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.479

High

941923

MAVS
Mitochondrial antiviral-signaling protein

1

1

High-throughput

0.479

High

941943

IPO4
Importin-4

1

1

High-throughput

0.479

High

941944

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.479

High

941946

UBXN4
UBX domain-containing protein 4

1

1

High-throughput

0.479

High

941947

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.479

High

941948

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

941950

TNPO1
Transportin-1

1

1

High-throughput

0.479

High

941956

FAF2
FAS-associated factor 2

1

1

High-throughput

0.479

High

941957

FACR2
Fatty acyl-CoA reductase 2

1

1

High-throughput

0.479

High

941975

MDN1
Midasin

1

1

High-throughput

0.479

High

941986

DIC
Mitochondrial dicarboxylate carrier

1

1

High-throughput

0.479

High

48576

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.458

High

941984

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.458

High

941985

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

135565

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.458

High

142089

PEX12
Peroxisome assembly protein 12

1

0

High-throughput

0.458

High

182946

NKRF
NF-kappa-B-repressing factor

1

0

High-throughput

0.458

High

210904

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.458

High

354454

PX11B
Peroxisomal membrane protein 11B

1

0

High-throughput

0.458

High

359625

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.458

High

385600

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

417348

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

588332

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

611056

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

651773

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.458

High

656085

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.458

High

695061

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

766360

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

784563

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

786043

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

788878

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.458

High

809987

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

840658

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

841670

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

860102

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.458

High

895523

SERPH
Serpin H1

1

0

High-throughput

0.458

High

896226

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.458

High

906385

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.458

High

919843

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

941888

TMM33
Transmembrane protein 33

1

0

High-throughput

0.458

High

941889

EPIPL
Epiplakin

1

0

High-throughput

0.458

High

941892

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

941893

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

941894

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.458

High

941898

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

941900

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.458

High

941902

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

941903

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.458

High

941904

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.458

High

941906

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

941913

NU188
Nucleoporin NUP188

1

0

High-throughput

0.458

High

941918

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

0

High-throughput

0.458

High

941924

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

941926

TM135
Transmembrane protein 135

1

0

High-throughput

0.458

High

941930

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.458

High

941934

AN13C
Ankyrin repeat domain-containing protein 13C

1

0

High-throughput

0.458

High

941935

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.458

High

941940

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

0

High-throughput

0.458

High

941949

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.458

High

941951

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

High-throughput

0.458

High

941954

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.458

High

941955

MARC2
Mitochondrial amidoxime reducing component 2

1

0

High-throughput

0.458

High

941958

CLP1L
Lipid scramblase CLPTM1L

1

0

High-throughput

0.458

High

941959

RBM15
RNA-binding protein 15

1

0

High-throughput

0.458

High

941961

PKP2
Plakophilin-2

1

0

High-throughput

0.458

High

941962

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.458

High

941963

LMF2
Lipase maturation factor 2

1

0

High-throughput

0.458

High

941964

DERL1
Derlin-1

1

0

High-throughput

0.458

High

941968

MFF
Mitochondrial fission factor

1

0

High-throughput

0.458

High

941971

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.458

High

941972

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

0

High-throughput

0.458

High

941973

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

941978

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.458

High

941981

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.458

High

941983

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.458

High

941988

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.458

High

941989

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.458

High

941992

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

941993

MYO5A
Unconventional myosin-Va

1

0

High-throughput

0.458

High

941994

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.458

High

941997

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.458

High

941998

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.458

High

941999

CEPT1
Choline/ethanolaminephosphotransferase 1

1

0

High-throughput

0.458

High

299126

FLOT1
Flotillin-1

1

1

High-throughput

0.445

High

538744

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

2

High-throughput

0.445

High

941982

SCN3B
Sodium channel regulatory subunit beta-3

1

1

High-throughput

0.445

High

941895

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

2

High-throughput

0.437

High

941908

UBE3C
Ubiquitin-protein ligase E3C

1

1

High-throughput

0.437

High

941931

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.437

High

941936

ACBD4
Acyl-CoA-binding domain-containing protein 4

1

1

High-throughput

0.437

High

941969

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.437

High

941974

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.437

High

941977

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.437

High

941987

XPO7
Exportin-7

1

1

High-throughput

0.437

High

941991

TDRKH
Tudor and KH domain-containing protein

1

2

High-throughput

0.437

High

248856

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

774246

BASI
Basigin

1

0

High-throughput

0.426

High

941925

LDB1
LIM domain-binding protein 1

1

0

High-throughput

0.426

High

941953

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.426

High

941965

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.426

High

652182

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

2

High-throughput

0.407

High

941966

S39A8
Metal cation symporter ZIP8

1

1

High-throughput

0.407

High

260850

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

348444

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.279

Low

488300

PPBI
Intestinal-type alkaline phosphatase

1

0

High-throughput

0.279

Low

732966

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

941896

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

0

High-throughput

0.279

Low

941910

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

941942

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

941970

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

296658

AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase

1

0

High-throughput

0.249

Low

320958

SUN1
SUN domain-containing protein 1

1

0

High-throughput

0.249

Low

329239

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.249

Low

621458

HXK1
Hexokinase-1

1

0

High-throughput

0.249

Low

655756

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.249

Low

842704

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

High-throughput

0.249

Low

849442

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

High-throughput

0.249

Low

916214

TXTP
Tricarboxylate transport protein, mitochondrial

1

0

High-throughput

0.249

Low

941890

DEST
Destrin

1

0

High-throughput

0.249

Low

941897

STX5
Syntaxin-5

1

0

High-throughput

0.249

Low

941909

PCH2
Pachytene checkpoint protein 2 homolog

1

0

High-throughput

0.249

Low

941912

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.249

Low

941915

VP13D
Intermembrane lipid transfer protein VPS13D

1

0

High-throughput

0.249

Low

941919

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.249

Low

941920

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.249

Low

941921

MON2
Protein MON2 homolog

1

0

High-throughput

0.249

Low

941976

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low

941990

SNX6
Sorting nexin-6

1

0

High-throughput

0.249

Low

941995

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.249

Low

653220

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

679319

DNJB2
DnaJ homolog subfamily B member 2

1

0

High-throughput

0.232

Low

941916

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

941928

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.232

Low

941937

SPX3
Sugar phosphate exchanger 3

1

0

High-throughput

0.232

Low

941938

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025