HitPredict

Interactor 1: GTF2I (P78347)
General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosomal region 6 protein)
Gene: GTF2I

Interactor 2: KLF15 (Q9UIH9)
Krueppel-like factor 15 (Kidney-enriched krueppel-like factor)
Gene: KLF15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 416
+	Hs
		563776 GTF2I_HUMAN (1-998): 0: 1555: 100.00		ZNF3_HUMAN (127-318): 1.69e-71: 233: 8.00
+	Hs
		942158 GTF2I_HUMAN (1-998): 0: 1555: 100.00		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		316854 GTF2I_HUMAN (1-998): 0: 1555: 100.00		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		942241 GTF2I_HUMAN (1-998): 0: 1555: 100.00		KLF16_HUMAN (319-403): 9.02e-31: 120: 62.35