HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.654

The method score is based on:

Property Details
Experiments 9581761, 21653829, 37207277
Identification Methods two hybrid, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0048169 - regulation of long-term neuronal synaptic plasticity
GO:0098978 - glutamatergic synapse
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 724
Hs

1 1343
+ Mm
+ Rn
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+ Hs
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Last updated: 15 Jul 2024