HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: FZD1 (Q9UP38)
Frizzled-1 (Fz-1) (hFz1) (FzE1)
Gene: FZD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	12067714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 647
+	Mm
		250809 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD1_MOUSE (1-647): 0: 867: 93.66
+	Hs
		254162 DLG4_HUMAN (1-724): 0: 667: 100.00		FZD7_HUMAN (100-647): 0: 774: 78.69
+	Mm
		1142150 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD7_MOUSE (74-647): 0: 772: 75.65
+	Hs
		942341 DLG4_HUMAN (1-724): 0: 667: 100.00		FZD2_HUMAN (101-647): 0: 762: 79.24
+	Mm
		1143526 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD2_MOUSE (101-647): 0: 761: 79.24
+	Hs
		942397 DLG4_HUMAN (1-724): 0: 667: 100.00		FZD4_HUMAN (81-642): 0: 622: 42.00
+	Mm
		1142145 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD4_MOUSE (76-642): 0: 617: 41.73
+	Mm
		250810 DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54		FZD1_MOUSE (1-647): 0: 867: 93.66
+	Mm
		250811 DLG2_MOUSE (225-474): 1.48e-18: 92.5: 21.09		FZD1_MOUSE (1-647): 0: 867: 93.66
+	Mm
		1142152 DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54		FZD7_MOUSE (74-647): 0: 772: 75.65
+	Mm
		1142153 DLG2_MOUSE (225-474): 1.48e-18: 92.5: 21.09		FZD7_MOUSE (74-647): 0: 772: 75.65
+	Mm
		1142147 DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54		FZD4_MOUSE (76-642): 0: 617: 41.73
+	Mm
		1142148 DLG2_MOUSE (225-474): 1.48e-18: 92.5: 21.09		FZD4_MOUSE (76-642): 0: 617: 41.73