Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: SHAN2 (Q9UPX8)
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)
Gene: SHANK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 10844022, 10527873
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~SH3_2, PDZ~PDZ_6, PDZ~SAM_1, PDZ~SH3_2, Ank_2~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007612 - learning
GO:0014069 - postsynaptic density
GO:0035176 - social behavior
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 724
Hs

1 1849
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Rn
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Dm
+ Rn
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024