HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	9115257, 21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031594 - neuromuscular junction GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 992
+	Mm
		69918 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP4_MOUSE (1-992): 0: 1229: 96.88
+	Rn
		677778 DLG4_RAT (1-724): 0: 668: 99.86		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Hs
		145945 DLG4_HUMAN (1-724): 0: 667: 100.00		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Rn
		677775 DLG4_RAT (1-724): 0: 668: 99.86		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Mm
		1143504 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		677776 DLG4_RAT (1-724): 0: 668: 99.86		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Mm
		1143394 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP2_MOUSE (1-992): 0: 1070: 41.73
+	Hs
		942392 DLG4_HUMAN (1-724): 0: 667: 100.00		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Mm
		936189 DLG3_MOUSE (20-724): 0: 583: 64.08		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Hs
		327234 DLG4_HUMAN (1-724): 0: 667: 100.00		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Mm
		1143344 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP3_MOUSE (1-992): 0: 970: 35.75
+	Rn
		677777 DLG4_RAT (1-724): 0: 668: 99.86		DLGP3_RAT (1-992): 0: 962: 35.20
+	Hs
		1132902 MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Rn
		957008 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Rn
		956989 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Rn
		957000 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Hs
		1132899 MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4618 MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Rn
		957005 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP3_RAT (1-992): 0: 962: 35.20
+	Mm
		1143445 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP5_MOUSE (521-935): 1.84e-100: 335: 17.10