HitPredict

Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Interactor 2: RBM8A (Q9Y5S9)
RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Gene: RBM8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.790

The method score is based on:

Property Details
Experiments 23602568
Identification Methods affinity chromatography technology, enzymatic study, tandem affinity purification, protein kinase assay
Interaction Type physical association, direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024