Protein: RIOK2
Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)

Gene: RIOK2
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q9BVS4

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

908126

RS16
Small ribosomal subunit protein uS9

1

5

High-throughput

0.691

High

1102168

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

4

High-throughput

0.691

High

1046944

BYST
Bystin

3

4

High-throughput

0.662

High

1253118

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

2

1

High-throughput

0.611

High

1314177

HECD1
E3 ubiquitin-protein ligase HECTD1

2

3

Small-scale

0.611

High

1054092

GRB7
Growth factor receptor-bound protein 7

2

1

High-throughput

0.571

High

934439

CSK21
Casein kinase II subunit alpha

1

7

High-throughput

0.569

High

950269

SMAD3
Mothers against decapentaplegic homolog 3

1

1

High-throughput

0.541

High

1298985

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.541

High

117808

MYO1C
Unconventional myosin-Ic

1

3

High-throughput

0.536

High

260996

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.536

High

446775

SNRPA
U1 small nuclear ribonucleoprotein A

1

5

High-throughput

0.536

High

455829

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.536

High

470145

H2AZ
Histone H2A.Z

1

4

High-throughput

0.536

High

586953

CSK22
Casein kinase II subunit alpha'

1

7

High-throughput

0.536

High

805784

RL27A
Large ribosomal subunit protein uL15

1

1

High-throughput

0.536

High

863997

CLH2
Clathrin heavy chain 2

1

2

High-throughput

0.536

High

879332

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

4

High-throughput

0.536

High

907490

RS8
Small ribosomal subunit protein eS8

1

4

High-throughput

0.536

High

911240

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.536

High

911500

RS11
Small ribosomal subunit protein uS17

1

4

High-throughput

0.536

High

916820

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.536

High

951900

SERF2
Small EDRK-rich factor 2

1

1

High-throughput

0.536

High

962330

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.536

High

967405

EWS
RNA-binding protein EWS

1

1

High-throughput

0.536

High

1024084

ACACA
Acetyl-CoA carboxylase 1

1

4

High-throughput

0.536

High

1030460

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.536

High

1049634

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

High-throughput

0.536

High

1079143

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.536

High

1085048

DREB
Drebrin

1

1

High-throughput

0.536

High

1087095

H2A2C
Histone H2A type 2-C

1

1

High-throughput

0.536

High

1205205

CD20B
Cell division cycle protein 20 homolog B

1

4

High-throughput

0.536

High

1292024

LTV1
Protein LTV1 homolog

1

2

High-throughput

0.536

High

1302017

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.536

High

1312225

H2AJ
Histone H2A.J

1

1

High-throughput

0.536

High

1314159

NSRP1
Nuclear speckle splicing regulatory protein 1

1

2

High-throughput

0.536

High

1314167

ABCF3
ATP-binding cassette sub-family F member 3

1

2

High-throughput

0.536

High

1314175

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

2

High-throughput

0.536

High

1314178

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1314179

NOB1
RNA-binding protein NOB1

1

4

High-throughput

0.536

High

1314181

RTRAF
RNA transcription, translation and transport factor protein

1

1

High-throughput

0.536

High

1314182

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

1

High-throughput

0.536

High

978881

TF65
Transcription factor p65

1

0

High-throughput

0.518

High

1044326

FCL
GDP-L-fucose synthase

1

0

High-throughput

0.518

High

264740

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

High-throughput

0.513

High

275598

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

0

High-throughput

0.513

High

360364

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

448804

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

687049

FOXN2
Forkhead box protein N2

1

0

High-throughput

0.513

High

813721

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

887605

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1121702

LBH
Protein LBH

1

0

High-throughput

0.513

High

1131395

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.513

High

1133758

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.513

High

1152689

JADE1
Protein Jade-1

1

0

High-throughput

0.513

High

1170341

CAN12
Calpain-12

1

0

High-throughput

0.513

High

1233536

MINK1
Misshapen-like kinase 1

1

0

High-throughput

0.513

High

1266947

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.513

High

1298964

BIRC8
Baculoviral IAP repeat-containing protein 8

1

0

High-throughput

0.513

High

1300485

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

1314170

BCLF1
Bcl-2-associated transcription factor 1

1

0

High-throughput

0.513

High

1314173

RALY
RNA-binding protein Raly

1

0

High-throughput

0.513

High

1314174

FBX5
F-box only protein 5

1

0

High-throughput

0.513

High

1314176

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.513

High

1314183

SPIN1
Spindlin-1

1

0

High-throughput

0.513

High

395654

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

1136761

MTCL3
Microtubule cross-linking factor 3

1

2

High-throughput

0.489

High

1312601

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.489

High

163218

XPO1
Exportin-1

1

8

High-throughput

0.479

High

228558

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

233884

HBP1
HMG box-containing protein 1

1

1

High-throughput

0.479

High

295211

RECQ4
ATP-dependent DNA helicase Q4

1

12

High-throughput

0.479

High

338930

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

347784

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

374809

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

599722

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

4

Small-scale

0.479

High

738012

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

High-throughput

0.479

High

817741

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

1

High-throughput

0.479

High

824346

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

882537

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.479

High

959649

VIGLN
Vigilin

1

4

High-throughput

0.479

High

1021640

TAF10
Transcription initiation factor TFIID subunit 10

1

1

High-throughput

0.479

High

1025537

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

3

High-throughput

0.479

High

1035577

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.479

High

1059840

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

1064101

TNIP1
TNFAIP3-interacting protein 1

1

5

High-throughput

0.479

High

1064674

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1129221

NKAPL
NKAP-like protein

1

1

High-throughput

0.479

High

1153914

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1188807

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1201896

TAXB1
Tax1-binding protein 1

1

3

High-throughput

0.479

High

1234430

NKAP
NF-kappa-B-activating protein

1

1

High-throughput

0.479

High

1240957

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1314162

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

1314163

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1314165

CENPJ
Centromere protein J

1

2

High-throughput

0.479

High

1314168

TXN4B
Thioredoxin-like protein 4B

1

1

Small-scale

0.479

High

1314169

TBA8
Tubulin alpha-8 chain

1

3

High-throughput

0.479

High

1314171

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1314164

PRD16
Histone-lysine N-methyltransferase PRDM16

1

0

High-throughput

0.460

High

48487

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.458

High

653159

DCK
Deoxycytidine kinase

1

0

High-throughput

0.458

High

1082957

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

1266741

RTF1
RNA polymerase-associated protein RTF1 homolog

1

0

High-throughput

0.458

High

47458

RPSA2
Small ribosomal subunit protein uS2B

1

7

High-throughput

0.445

High

1245630

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

1

High-throughput

0.445

High

1314166

SLX9
Ribosome biogenesis protein SLX9 homolog

1

1

High-throughput

0.445

High

1314180

RL26L
Ribosomal protein uL24-like

1

4

High-throughput

0.437

High

995581

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.426

High

1233184

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1190925

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

299204

CSCL1
CSC1-like protein 1

1

0

High-throughput

0.279

Low

388030

AMYP
Pancreatic alpha-amylase

1

0

High-throughput

0.279

Low

1314160

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

1314161

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.279

Low

1314172

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.279

Low

1314184

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

263100

RM33
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.249

Low

537227

CX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024