Interactor 1: JAG1 (P78504)
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)
Gene: JAG1

Interactor 2: ADA17 (P78536)
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b)
Gene: ADAM17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 23375636
Identification Methods cleavage assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005112 - Notch binding
GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
GO:0016020 - membrane
GO:0016324 - apical plasma membrane
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1218
Hs

1 824
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024