Interactor 1: JAG1 (P78504)
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)
Gene: JAG1
Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.76 | 1.00 | 0.876 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | DSL~EGF_CA, EGF~EGF, EGF~EGF_CA, EGF_CA~EGF_CA, EGF_CA~MNNL |
Common GO terms | GO:0001709 - cell fate determination GO:0002011 - morphogenesis of an epithelial sheet GO:0003184 - pulmonary valve morphogenesis GO:0005112 - Notch binding GO:0005509 - calcium ion binding and 9 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024