HitPredict

Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Interactor 2: STYK1 (Q6J9G0)
Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)
Gene: STYK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 4128 Hs			1 422
+	Hs
		609246 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		FGFR3_HUMAN (10-409): 1.6e-125: 383: 27.01
+	Hs
		601494 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		FGFR2_HUMAN (29-417): 7.84e-125: 382: 23.64
+	Hs
		665578 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		EPHB2_HUMAN (5-393): 2.02e-120: 376: 19.29
+	Hs
		337429 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		ABL1_HUMAN (143-387): 8.6e-41: 156: 35.34
+	Hs
		944192 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		TIE2_HUMAN (146-380): 2.39e-34: 137: 31.56
+	Hs
		872435 ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42		EPHA5_HUMAN (2-408): 4.94e-121: 377: 20.33
+	Hs
		337382 MTOR_HUMAN (2776-4127): 0: 695: 15.99		ABL1_HUMAN (143-387): 8.6e-41: 156: 35.34
+	Hs
		337460 ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42		ABL1_HUMAN (143-387): 8.6e-41: 156: 35.34
+	Hs
		337465 ATR_HUMAN (3377-4128): 2.05e-122: 438: 19.28		ABL1_HUMAN (143-387): 8.6e-41: 156: 35.34