HitPredict

Interactor 1: P79922 (P79922)
DNA (cytosine-5)-methyltransferase (EC 2.1.1.37)
Gene: dnmt1.L

Interactor 2: CDK8 (Q66KH9)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit cdk8) (Mediator of RNA polymerase II transcription subunit cdk8)
Gene: CDK8

Species: Xenopus laevis

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32144273
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1490 Xl			1 416
+	Xl
		724504 P79922_XENLA (1-1490): 0: 1936: 100.00		CDK1A_XENLA (26-287): 1.23e-37: 140: 35.64
+	Xl
		621605 P79922_XENLA (1-1490): 0: 1936: 100.00		CDK1B_XENLA (26-287): 1.89e-37: 139: 35.64
+	Hs
		625122 DNMT1_HUMAN (2-217): 9.57e-47: 187: 41.78		CDK2_HUMAN (23-297): 7.01e-117: 344: 31.61
+	Hs
		625481 Q59FP7_HUMAN (5-217): 4.79e-46: 184: 41.48		CDK2_HUMAN (23-297): 7.01e-117: 344: 31.61
+	Hs
		641195 DNMT1_HUMAN (2-217): 9.57e-47: 187: 41.78		CDK5_HUMAN (26-287): 2.5e-38: 141: 33.01