HitPredict

Interactor 1: CCL8 (P80075)
C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Gene: CCL8

Interactor 2: XCL2 (Q9UBD3)
Cytokine SCM-1 beta (C motif chemokine 2) (XC chemokine ligand 2)
Gene: XCL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0002548 - monocyte chemotaxis
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0007165 - signal transduction
GO:0007186 - G protein-coupled receptor signaling pathway
and 10 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 99
Hs

1 114
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Last updated: 15 Jul 2024