HitPredict

Interactor 1: DLK1 (P80370)
Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]
Gene: DLK1

Interactor 2: ANR27 (Q96NW4)
Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein)
Gene: ANKRD27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 383 Hs			1 1050
+	Hs
		980449 NOTC2_HUMAN (10-316): 6e-28: 118: 23.61		ANR44_HUMAN (98-809): 7.29e-79: 280: 12.72
+	Hs
		1167037 FAT4_HUMAN (57-157): 5.65e-11: 66.7: 23.76		TNKS2_HUMAN (107-816): 5.68e-95: 329: 15.46
+	Hs
		804293 NOTC1_HUMAN (6-314): 3.86e-22: 100: 22.02		ANR44_HUMAN (98-809): 7.29e-79: 280: 12.72
+	Hs
		166914 NOTC2_HUMAN (10-316): 6e-28: 118: 23.61		ANR28_HUMAN (86-614): 2.41e-71: 259: 18.43
+	Hs
		1237561 NOTC3_HUMAN (22-244): 1.94e-17: 86.7: 31.37		ANR44_HUMAN (98-809): 7.29e-79: 280: 12.72
+	Hs
		167042 NOTC3_HUMAN (22-244): 1.94e-17: 86.7: 31.37		ANR28_HUMAN (86-614): 2.41e-71: 259: 18.43
+	Dm
		65546 NOTCH_DROME (132-340): 2.73e-17: 85.9: 23.36		A8JNM5_DROME (596-1040): 2.1e-67: 251: 14.89
+	Dm
		246781 TENM_DROME (164-354): 9.9e-24: 105: 12.92		Q0KIE7_DROME (609-1028): 1.07e-59: 226: 14.03