Protein: NEK7
Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)

Gene: NEK7
Organism: Homo sapiens
Interactions: 222
UniProt ID: Q8TDX7

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1255579

NLRP3
NACHT, LRR and PYD domains-containing protein 3

9

3

Small-scale

0.969

High

1255598

NEK6
Serine/threonine-protein kinase Nek6

6

16

High-throughput

0.950

High

1254355

NEK9
Serine/threonine-protein kinase Nek9

5

18

Small-scale

0.934

High

1147963

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

3

5

High-throughput

0.871

High

1173306

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

3

14

High-throughput

0.871

High

1197674

NEK8
Serine/threonine-protein kinase Nek8

2

18

High-throughput

0.811

High

1255565

ZN669
Zinc finger protein 669

2

4

High-throughput

0.811

High

309503

MTMR5
Myotubularin-related protein 5

1

4

High-throughput

0.691

High

398735

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

2

High-throughput

0.691

High

538329

ENPL
Endoplasmin

1

20

High-throughput

0.691

High

831007

CTCF
Transcriptional repressor CTCF

1

8

High-throughput

0.691

High

942823

SRPK2
SRSF protein kinase 2

1

15

High-throughput

0.691

High

972555

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

14

High-throughput

0.691

High

1084540

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

7

High-throughput

0.691

High

1255557

PSPC1
Paraspeckle component 1

1

12

High-throughput

0.691

High

1255560

RREB1
Ras-responsive element-binding protein 1

1

4

High-throughput

0.691

High

1255577

SCYL1
N-terminal kinase-like protein

1

17

High-throughput

0.691

High

1255583

DNJC2
DnaJ homolog subfamily C member 2

1

7

High-throughput

0.691

High

1255594

BICC1
Protein bicaudal C homolog 1

1

20

High-throughput

0.691

High

1255595

ZN556
Zinc finger protein 556

1

7

High-throughput

0.691

High

1255601

ZN331
Zinc finger protein 331

1

6

High-throughput

0.691

High

1255611

ZN214
Zinc finger protein 214

1

6

High-throughput

0.691

High

1255615

G3BP2
Ras GTPase-activating protein-binding protein 2

1

3

High-throughput

0.691

High

928409

DYL1
Dynein light chain 1, cytoplasmic

3

6

High-throughput

0.675

High

156619

PPE1
Serine/threonine-protein phosphatase with EF-hands 1

1

20

High-throughput

0.665

High

841556

RASF2
Ras association domain-containing protein 2

1

15

High-throughput

0.665

High

856097

RBM5
RNA-binding protein 5

1

9

High-throughput

0.665

High

1110300

SP6
Transcription factor Sp6

1

11

High-throughput

0.665

High

1192134

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

11

High-throughput

0.665

High

1192440

Q7Z780
U2 small nuclear RNA auxiliary factor 1

1

1

High-throughput

0.665

High

1231084

ARG28
Rho guanine nucleotide exchange factor 28

1

6

High-throughput

0.665

High

1255575

SPF45
Splicing factor 45

1

3

High-throughput

0.665

High

1255599

MYNN
Myoneurin

1

5

High-throughput

0.665

High

1255606

TSAP1
tRNA selenocysteine 1-associated protein 1

1

4

High-throughput

0.665

High

1255613

TPX2
Targeting protein for Xklp2

1

3

High-throughput

0.665

High

1255556

NEK7
Serine/threonine-protein kinase Nek7

1

16

Small-scale

0.647

High

1104135

EMAL3
Echinoderm microtubule-associated protein-like 3

2

11

High-throughput

0.628

High

1255597

EMAL4
Echinoderm microtubule-associated protein-like 4

2

10

Small-scale

0.619

High

1244030

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

5

High-throughput

0.618

High

129029

PLK4
Serine/threonine-protein kinase PLK4

1

16

Small-scale

0.618

High

228149

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.618

High

779785

CCNF
Cyclin-F

1

9

High-throughput

0.618

High

861857

PLK1
Serine/threonine-protein kinase PLK1

1

17

High-throughput

0.618

High

1170948

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.618

High

1255593

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.618

High

180068

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

2

0

High-throughput

0.602

High

58549

MBPHL
Myosin-binding protein H-like

1

1

High-throughput

0.594

High

897925

RAP1B
Ras-related protein Rap-1b

1

4

High-throughput

0.594

High

1044483

RAB31
Ras-related protein Rab-31

1

5

High-throughput

0.594

High

1255568

RAB3C
Ras-related protein Rab-3C

1

2

High-throughput

0.594

High

723360

APJ
Apelin receptor

1

0

High-throughput

0.578

High

423307

PDIA1
Protein disulfide-isomerase

2

3

High-throughput

0.574

High

1255617

LAMP3
Lysosome-associated membrane glycoprotein 3

2

4

High-throughput

0.574

High

869692

TERF1
Telomeric repeat-binding factor 1

1

0

Small-scale

0.561

High

124022

SPT5H
Transcription elongation factor SPT5

1

1

High-throughput

0.536

High

131011

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.536

High

229708

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

17

High-throughput

0.536

High

438965

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

1

High-throughput

0.536

High

444917

ANXA5
Annexin A5

1

6

High-throughput

0.536

High

514050

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

2

High-throughput

0.536

High

517379

PCNA
Proliferating cell nuclear antigen

1

4

High-throughput

0.536

High

524992

XRCC5
X-ray repair cross-complementing protein 5

1

3

High-throughput

0.536

High

531221

EF2
Elongation factor 2

1

8

High-throughput

0.536

High

547150

EZRI
Ezrin

1

8

High-throughput

0.536

High

571034

PYRG1
CTP synthase 1

1

1

High-throughput

0.536

High

607120

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

1

High-throughput

0.536

High

616066

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

627311

MCM3
DNA replication licensing factor MCM3

1

7

High-throughput

0.536

High

652929

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.536

High

666944

TKT
Transketolase

1

6

High-throughput

0.536

High

670741

PRDX6
Peroxiredoxin-6

1

8

High-throughput

0.536

High

702949

KINH
Kinesin-1 heavy chain

1

4

High-throughput

0.536

High

713564

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

2

High-throughput

0.536

High

727293

NU214
Nuclear pore complex protein Nup214

1

10

High-throughput

0.536

High

785715

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

5

High-throughput

0.536

High

794283

MSH2
DNA mismatch repair protein Msh2

1

3

High-throughput

0.536

High

796777

RANG
Ran-specific GTPase-activating protein

1

4

High-throughput

0.536

High

825856

NASP
Nuclear autoantigenic sperm protein

1

3

High-throughput

0.536

High

826018

FAS
Fatty acid synthase

1

3

High-throughput

0.536

High

829192

SYAC
Alanine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

838668

GDIB
Rab GDP dissociation inhibitor beta

1

1

High-throughput

0.536

High

852740

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

2

High-throughput

0.536

High

862442

ACLY
ATP-citrate synthase

1

2

High-throughput

0.536

High

873055

KAD2
Adenylate kinase 2, mitochondrial

1

2

High-throughput

0.536

High

896156

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.536

High

896500

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

4

High-throughput

0.536

High

901398

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.536

High

902681

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.536

High

929334

IF5A1
Eukaryotic translation initiation factor 5A-1

1

2

High-throughput

0.536

High

965205

CAP1
Adenylyl cyclase-associated protein 1

1

1

High-throughput

0.536

High

981090

LGUL
Lactoylglutathione lyase

1

1

High-throughput

0.536

High

985366

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.536

High

1044558

FHL1
Four and a half LIM domains protein 1

1

4

High-throughput

0.536

High

1052717

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

16

High-throughput

0.536

High

1057328

SMC1A
Structural maintenance of chromosomes protein 1A

1

20

High-throughput

0.536

High

1063347

CND1
Condensin complex subunit 1

1

1

High-throughput

0.536

High

1078120

AAAT
Neutral amino acid transporter B(0)

1

2

High-throughput

0.536

High

1138988

GP107
Protein GPR107

1

1

High-throughput

0.536

High

1158551

L2GL2
LLGL scribble cell polarity complex component 2

1

2

High-throughput

0.536

High

1162615

LARP1
La-related protein 1

1

4

High-throughput

0.536

High

1205474

PALB2
Partner and localizer of BRCA2

1

1

High-throughput

0.536

High

1255558

DDX1
ATP-dependent RNA helicase DDX1

1

8

High-throughput

0.536

High

1255559

GCN1
Stalled ribosome sensor GCN1

1

12

High-throughput

0.536

High

1255561

HDAC2
Histone deacetylase 2

1

9

High-throughput

0.536

High

1255564

FUBP2
Far upstream element-binding protein 2

1

15

High-throughput

0.536

High

1255566

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.536

High

1255574

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.536

High

1255581

TBCB
Tubulin-folding cofactor B

1

10

High-throughput

0.536

High

1255585

CPNE1
Copine-1

1

4

High-throughput

0.536

High

1255602

SMC4
Structural maintenance of chromosomes protein 4

1

12

High-throughput

0.536

High

1255603

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.536

High

1255604

S39A9
Zinc transporter ZIP9

1

2

High-throughput

0.536

High

1255607

EHD2
EH domain-containing protein 2

1

4

High-throughput

0.536

High

1255610

SAE2
SUMO-activating enzyme subunit 2

1

1

High-throughput

0.536

High

1255616

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

4

High-throughput

0.536

High

340498

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.530

High

121196

LEG8
Galectin-8

1

2

High-throughput

0.515

High

257386

CNOT3
CCR4-NOT transcription complex subunit 3

1

4

High-throughput

0.515

High

259298

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

6

High-throughput

0.515

High

302349

CMTA2
Calmodulin-binding transcription activator 2

1

8

High-throughput

0.515

High

428328

TBB5
Tubulin beta chain

1

16

High-throughput

0.515

High

449322

LEG1
Galectin-1

1

2

High-throughput

0.515

High

451024

GNAO

1

3

High-throughput

0.515

High

534429

3BHS1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

1

1

High-throughput

0.515

High

795703

MAGA2
Melanoma-associated antigen 2

1

2

High-throughput

0.515

High

798720

PRS6B
26S proteasome regulatory subunit 6B

1

6

High-throughput

0.515

High

973965

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

11

High-throughput

0.515

High

1027732

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

3

High-throughput

0.515

High

1034101

TCOF
Treacle protein

1

18

High-throughput

0.515

High

1190036

MAVS
Mitochondrial antiviral-signaling protein

1

9

High-throughput

0.515

High

1231834

PIAS4
E3 SUMO-protein ligase PIAS4

1

2

High-throughput

0.515

High

1240443

POC1A
POC1 centriolar protein homolog A

1

7

High-throughput

0.515

High

1255567

DDT4L
DNA damage-inducible transcript 4-like protein

1

3

High-throughput

0.515

High

1255590

THAP7
THAP domain-containing protein 7

1

2

High-throughput

0.515

High

1255619

PYGO1
Pygopus homolog 1

1

3

High-throughput

0.515

High

1255621

SERC
Phosphoserine aminotransferase

1

1

High-throughput

0.515

High

156041

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

0

High-throughput

0.513

High

606460

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.513

High

867236

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

1088164

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1190749

DCXR
L-xylulose reductase

1

0

High-throughput

0.513

High

1255562

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1255563

GSLG1
Golgi apparatus protein 1

1

0

High-throughput

0.513

High

1255571

DPH3
Diphthamide biosynthesis protein 3

1

0

High-throughput

0.513

High

1255572

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.513

High

1255582

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

1255588

PDD2L
Programmed cell death protein 2-like

1

0

High-throughput

0.513

High

276666

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

High-throughput

0.493

High

822782

T23O
Tryptophan 2,3-dioxygenase

1

0

High-throughput

0.493

High

824953

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.493

High

1147435

TPGS2
Tubulin polyglutamylase complex subunit 2

1

0

High-throughput

0.493

High

1222447

DRC7
Dynein regulatory complex subunit 7

1

0

High-throughput

0.493

High

1241441

NF2IP
NFATC2-interacting protein

1

0

High-throughput

0.493

High

1255570

MMAB
Corrinoid adenosyltransferase MMAB

1

0

High-throughput

0.493

High

1255573

FAH2A
Fumarylacetoacetate hydrolase domain-containing protein 2A

1

0

High-throughput

0.493

High

1255578

SPT17
Spermatogenesis-associated protein 17

1

0

High-throughput

0.493

High

1255592

TNMD
Tenomodulin

1

0

High-throughput

0.493

High

1255612

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.493

High

150245

AP3D1
AP-3 complex subunit delta-1

1

7

High-throughput

0.489

High

164979

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.489

High

314362

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

3

High-throughput

0.489

High

417748

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.489

High

1056222

I13R2
Interleukin-13 receptor subunit alpha-2

1

11

High-throughput

0.489

High

1067772

PDIA6
Protein disulfide-isomerase A6

1

5

High-throughput

0.489

High

1083126

DPYL2
Dihydropyrimidinase-related protein 2

1

2

High-throughput

0.489

High

1139365

ULBP6
UL16-binding protein 6

1

5

High-throughput

0.489

High

1192601

FLIP1
Filamin-A-interacting protein 1

1

20

High-throughput

0.489

High

1219509

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.489

High

1255600

LUC7L
Putative RNA-binding protein Luc7-like 1

1

1

High-throughput

0.489

High

1255608

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

1255618

LC7L2
Putative RNA-binding protein Luc7-like 2

1

1

High-throughput

0.489

High

1255620

PCDGD
Protocadherin gamma-B1

1

4

High-throughput

0.489

High

317996

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

8

High-throughput

0.479

High

331851

NSD2
Histone-lysine N-methyltransferase NSD2

1

7

Small-scale

0.479

High

347408

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

599696

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

8

Small-scale

0.479

High

651764

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

667479

CASP1
Caspase-1

1

5

Small-scale

0.479

High

720986

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

724002

CBS
Cystathionine beta-synthase

1

1

High-throughput

0.479

High

786033

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

5

High-throughput

0.479

High

1042116

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1087916

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

17

High-throughput

0.479

High

1188600

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1204897

TRI50
E3 ubiquitin-protein ligase TRIM50

1

6

Small-scale

0.479

High

1243813

WDR19
WD repeat-containing protein 19

1

14

High-throughput

0.479

High

1255596

IF122
Intraflagellar transport protein 122 homolog

1

11

High-throughput

0.479

High

1255609

WDR35
WD repeat-containing protein 35

1

9

High-throughput

0.479

High

1255614

ASC
Apoptosis-associated speck-like protein containing a CARD

1

4

Small-scale

0.479

High

48849

A0JP07
KIAA1683 protein

1

2

High-throughput

0.470

High

100178

F6Y2X3
Tafazzin family protein

1

1

High-throughput

0.470

High

644610

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

5

High-throughput

0.470

High

734385

CXA5
Gap junction alpha-5 protein

1

2

High-throughput

0.470

High

832860

TSP3
Thrombospondin-3

1

6

High-throughput

0.470

High

945209

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

6

High-throughput

0.470

High

1166597

CREL2
Protein disulfide isomerase CRELD2

1

6

High-throughput

0.470

High

1191400

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

5

High-throughput

0.470

High

1255576

TMX3
Protein disulfide-isomerase TMX3

1

5

High-throughput

0.470

High

1255580

PRAM
PML-RARA-regulated adapter molecule 1

1

10

High-throughput

0.470

High

1255586

EGFL8
Epidermal growth factor-like protein 8

1

6

High-throughput

0.470

High

961206

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1062427

PAF15
PCNA-associated factor

1

0

High-throughput

0.458

High

1255591

SHRPN
Sharpin

1

0

Small-scale

0.458

High

352665

TNFA
Tumor necrosis factor

2

0

High-throughput

0.318

High

396484

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1058492

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.279

Low

1100097

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1131245

NU188
Nucleoporin NUP188

1

0

High-throughput

0.279

Low

1255584

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.279

Low

560136

EPCAM
Epithelial cell adhesion molecule

1

0

High-throughput

0.268

Low

1014676

FUT2
Galactoside alpha-(1,2)-fucosyltransferase 2

1

0

High-throughput

0.268

Low

1159713

PBIR3
PABIR family member 1

1

0

High-throughput

0.268

Low

1160096

LEG1H
Protein LEG1 homolog

1

0

High-throughput

0.268

Low

1231939

NXPE1
NXPE family member 1

1

0

High-throughput

0.268

Low

1241863

MFI
Protein MFI

1

0

High-throughput

0.268

Low

1250861

CA216
UPF0500 protein C1orf216

1

0

High-throughput

0.268

Low

1251846

Q8TB02
MGC39372 protein

1

0

High-throughput

0.268

Low

1255569

ZHX1R
Zinc fingers and homeoboxes protein 1, isoform 2

1

0

High-throughput

0.268

Low

1255587

Q9BQ29
THAP4 protein

1

0

High-throughput

0.268

Low

1255605

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.268

Low

1255589

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024