Interactor 1: PTPR2 (P80560)
Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.-) (EC 3.1.3.48) (PTP IA-2beta) (Phogrin) (Protein tyrosine phosphatase-NP) (PTP-NP) [Cleaved into: IA-2beta71; IA-2beta64; IA-2beta60]
Gene: Ptprn2
Interactor 2: PTPRN (Q60673)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.42 | 1.00 | 0.653 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12364328 |
| Identification Methods | anti tag coimmunoprecipitation, two hybrid |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Receptor_IA-2~Receptor_IA-2, Y_phosphatase~Y_phosphatase |
| Common GO terms | GO:0030141 - secretory granule GO:0035773 - insulin secretion involved in cellular response to glucose stimulus GO:0045202 - synapse GO:0051046 - regulation of secretion |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
