Interactor 1: SIM1 (P81133)
Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14)
Gene: SIM1
Interactor 2: ARNT2 (Q9HBZ2)
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1)
Gene: ARNT2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 1.00 | 0.849 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27472814, 32296183, unassigned1304 |
| Identification Methods | fluorescent resonance energy transfer, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HLH~HLH, HLH~PAS, PAS~PAS, PAS~PAS_11, PAS~PAS_3, PAS_11~PAS_3 |
| Common GO terms | GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
