HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: 5HT4R (Q13639)
5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)
Gene: HTR4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 388
+	Hs
		835574 TSN7_HUMAN (1-234): 1.4e-56: 182: 22.31		5HT4R_HUMAN (1-388): 4.43e-103: 311: 100.00
+	Hs
		458357 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		ADRB2_HUMAN (13-386): 2.78e-81: 256: 32.55
+	Hs
		458315 TSN7_HUMAN (1-234): 1.4e-56: 182: 22.31		ADRB2_HUMAN (13-386): 2.78e-81: 256: 32.55
+	Hs
		770726 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		ADA1A_HUMAN (4-339): 2.19e-71: 232: 28.89
+	Hs
		458278 CD9_HUMAN (1-234): 7.49e-54: 174: 43.59		ADRB2_HUMAN (13-386): 2.78e-81: 256: 32.55
+	Hs
		221444 TSN15_HUMAN (10-230): 2.63e-44: 152: 15.48		OX2R_HUMAN (10-387): 5.47e-79: 251: 24.56
+	Hs
		349382 TSN15_HUMAN (10-230): 2.63e-44: 152: 15.48		NK3R_HUMAN (6-363): 1.49e-64: 214: 19.73