Protein: 5HT4R
5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)

Gene: 5HT4R, HTR4
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q13639

Gene Ontology (top 5):
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

186906

GPR37
Prosaposin receptor GPR37

1

17

High-throughput

0.752

High

1116391

5HT4R
5-hydroxytryptamine receptor 4

1

16

Small-scale

0.618

High

243859

GRIN2
G protein-regulated inducer of neurite outgrowth 2

1

0

High-throughput

0.558

High

483334

CLCB
Clathrin light chain B

1

3

High-throughput

0.541

High

693400

CERS1
Ceramide synthase 1

1

11

High-throughput

0.541

High

835574

TSN7
Tetraspanin-7

1

7

High-throughput

0.541

High

948817

CD81
CD81 antigen

1

7

High-throughput

0.541

High

1006965

CLD10
Claudin-10

1

3

High-throughput

0.541

High

1116394

MGLL
Monoglyceride lipase

1

3

High-throughput

0.541

High

1116396

ANO10
Anoctamin-10

1

2

High-throughput

0.541

High

1116397

S39A1
Zinc transporter ZIP1

1

9

High-throughput

0.541

High

1116398

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.541

High

1116399

TEFF2
Tomoregulin-2

1

4

High-throughput

0.541

High

1116392

TM230
Transmembrane protein 230

1

0

High-throughput

0.518

High

1116400

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.518

High

693236

GDF1
Embryonic growth/differentiation factor 1

1

1

High-throughput

0.494

High

1116395

GHITM
Growth hormone-inducible transmembrane protein

1

3

High-throughput

0.494

High

1116393

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025